Background: Adherence to prescribed medication is crucial part in myocardial infarction and prevent catastrophic complications unfortunately death. Aim of the study: Was to assess medications adherence for patients with myocardial infarction. Subjects and Methods: Research design: A descriptive design was adopted to carry out this study. Setting: The study was conducted at outpatient cardiac clinics at Zagazig University hospitals, Egypt. Subjects: A purposive sample of (100) patients with MI was conducted. Tools of data collection: Two tools were used, tool I: An Interview questionnaire about demographic characteristics and medical history of studied patients Tool II: adherence to refill and medication scale. Results: The current study revealed that (65%) were males with the mean age of all patients was 58.75±10.4, (70%) were educated, (87%) had scarce income, (52%) were smokers, the mean of disease duration per years was 4.2±3.5, (48%) had hypertension while (65%) were diabetic, (50%) organized follow up visit to outpatient's clinic each three months or earlier, finally, (82%) of the studied patients were adhere to cardiovascular medications with mean± SD (21.66±5.4). Conclusion: Studied patients with MI had adherence to cardiovascular medications. And gender, education, duration of the disease had relation to medication adherence. Recommendations Further studies to assess adherence of myocardial infarction patients to therapeutic regimen not medications only and factors affecting on adherence. Key words: Cardiovascular Medications, Adherence and Myocardial Infarction