Background: In a modern era of increased race and key technical variations. The enhancement of personal performance at work has a great concern by organizations and researchers. It is thought that individual performance can be rising to the organizational level, which aids to advance organizational performance and vie with others eventually. Employee’s performance can be educated and erudite by numerous approaches and materials such as shared lectures, emulations, and learning models. Furthermore, nurses have to utilize various self-education means, for example, brochures, handouts, or models to aid them in acting, modifying, and straighten their performance to proficient ones. Simultaneously, nurse managers should design, craft, and use those learning methods for coaching, guiding, instructing, and training staff nurses Aim: To construct contextual variables and nurses’ performance model at Zagazig University Hospitals (ZUH’s) in Egypt. The following research objectives werewritten to accomplish this aim: 1. Assess the performance of nurses inZUHs in Egypt. 2. Measure contextual variables(aspiration, autonomy, self-regulation, self-efficacy, role stress, role efficacy, supervisor task-oriented, andrelational leadership style, andsupervisor communicator competence) that can positively or negatively affect the nurses’ performance ZUH’s, Egypt 3. Explore the relationships amongthese variables and the nurses’ performance at ZUH’s in Egypt 4. Construct an efficient model Research design: The descriptive, cross-sectional and correlational designs were employed to meet the current study's aims Settings: This research was executed at Zagazig University Hospitals (ZUH’s) in Al˗Sharqia governorate, Egypt. Subjects: A stratified proportionate random sample (n = 300) of nurses from various classes was employed, as well as a jury committee (n = 9). Study tools: Data was collected using a 9- questionnaire format and opinion questionnaire sheets. Results: Structural equation modeling revealed a good fit of the model, χ2/df value < 5, GFI > 0.90, AGFI > 0.90, CFI > 0.90, TLI > 0.90, NFI > 0.90, and IFI > 0.90, RMSEA and RMR ≤ 0.08. There were statistically significant associations between nurses' performance and self-efficacy at the p- value.038, role efficacy at p-value0.010, job autonomy at p-value 0.039, career aspiration at p-value .012and organizational role stress at p-value.046. However, the relationship between perceived nurses' job performance and remaining influential factors is weak. Conclusion and recommendations: The contextual variables model affecting nurses' performance at ZUH’s in Egypt was created and validated. The suggested contextual variables model affecting nurses' performance should be used at ZUH’s in Egypt. Nurses have to self-regulate their work; nurses and nurse leaders have to implement the instructions and intervention measures for improving performance regarding the mode