SPIROHYDANTOINS DERIVED FROM 1-TETRALONE: DESIGN, SYNTHESIS AND EXPLORATION OF THEIR ANTICONVULSANT ACTIVITY AND NEUROTOXICITY

Faculty Veterinary Medicine Year: 2007
Type of Publication: ZU Hosted Pages:
Authors:
Sameh Mohamed Mostafa Elnbtete
Journal: Bulletin of Faculty of Pharmacy, Cairo University - Journal Springer Nature Volume:
Keywords : SPIROHYDANTOINS DERIVED FROM 1-TETRALONE: DESIGN, SYNTHESIS    
Abstract:
A series of spiro[imidazolidine-4,1`(2`H)-naphthalene]-2,5-diones was synthesized and evaluated for anticonvulsant activity in the maximal electroshock (MES) and subcutaneous pentylene-tetrazole (scPTZ) animal screens. Neurotoxicity was ass
    
     
 
       

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  • Sameh Mohamed Mostafa Elnbtete , "Synthesis and Pharmacological Studies for New Benzotriazole and Dibenzodiazepine Derivatives as Antipsychotic Agents", Springer Nature, 2009 More
  • Sameh Mohamed Mostafa Elnbtete , "Biological activities of new salts of 2-carboxyphenyloxamoylamino acids", Springer Nature, 2015 More
  • Sameh Mohamed Mostafa Elnbtete , "Design, synthesis, anticonvulsant activity, and pharmacophore study of new 1,5-diaryl-1H-1,2,4-triazole-3-carboxamide derivatives", Springer, 2017 More
  • Sameh Mohamed Mostafa Elnbtete , "Synthesis and Some Pharmacological Studies of New Benzenesulfonamide Derivatives", Springer Nature, 2002 More

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