Design, synthesis, anticonvulsant activity, and pharmacophore study of new 1,5-diaryl-1H-1,2,4-triazole-3-carboxamide derivatives

Faculty Veterinary Medicine Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Sameh Mohamed Mostafa Elnbtete
Journal: Medicinal Chemistry Research Springer Volume:
Keywords : Design, synthesis, anticonvulsant activity, , pharmacophore study    
Abstract:
Diaryl-1H-1,2,4-triazole-3-carboxamide derivatives were designed, synthesized, and evaluated for its anticonvulsant activity using maximal electroshock (MES) and chemoshock (scPTZ and Strychnine) animal screen methods. Neurotoxicity was als
    
     
 
       

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  • Sameh Mohamed Mostafa Elnbtete , "دراسة مقارنة لاثنين من مضادات الاكسدة", لايوجد, 1900 More
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  • Sameh Mohamed Mostafa Elnbtete , "Biological activities of new salts of 2-carboxyphenyloxamoylamino acids", Springer Nature, 2015 More
  • Sameh Mohamed Mostafa Elnbtete , "Synthesis and Some Pharmacological Studies of New Benzenesulfonamide Derivatives", Springer Nature, 2002 More
  • Sameh Mohamed Mostafa Elnbtete , "Synthesis and Biological Activities of 2-Carboxyphenyloxamoylamino Acids, their Salts with 2-ethoxy-6,9-Diaminoacridine and D-glucosamine", Springer Nature, 2013 More

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