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Search Result For 'nephrotoxicity' , Result Number : 15

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Research Area
Ahmed Shaban Abdelaziz
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Aqueous extract of Alhagi Maurorum protects from norfloxacin-induced hepato-nephrotoxicity in rats
Taghreed Saber Mohamed Sayed Ahmd
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
nephrotoxicity
Mohammed Metwally Mohamed Metwallie
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
5. Curcumin alleviates colistin-induced nephrotoxicity and neurotoxicity in rats via attenuation of oxidative stress, inflammation and apoptosis. Chem Biol Interact. 2018; 294: 56-64
Mohammed Metwally Mohamed Metwallie
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Alpha-lipoic acid suppresses gibberellic acid nephrotoxicity in Nile tilapia (Oreochromis niloticus) via modulating oxidative stress, inflammation, cytokine production, and apoptosis
Arwa Ahmed Saad Hassan Saad Elsheikh
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Human kidney injury molecule-1 and interleukin-18 as predictive markers of nephrotoxicity in acute organophosphorus poisoned patients in Zagazig University hospitals
Eman Alsayed Hassan Mohamed Khayal
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Human kidney injury molecule-1 and interleukin-18 as predictive markers of nephrotoxicity in acute organophosphorus poisoned patients in Zagazig University hospitals
Doaa Mohamed Youseif Abdelhamed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Role of Pomegranate Peel Extract and N-Acetyl cysteine supplementation on Paracetamol-Induced Nephrotoxicity in Adult Male Albino Rats
Shimaa Hamed Amin Atia
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Study the protective role of Pomegranate Peel Extract and N-Acetyl cysteine supplementaton alone and in combination on Paracetamol induced Nephrotoxicity
Marwah elsayed Selim ali Mujahid
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
protective effect of salicylic acid againest gentamicin nephrotoxicity in rats
Nadya ebasiry Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
BACKGROUND: Gentamicin is widely used broad spectrum aminoglycoside antibiotic. Despite its beneficial effects, gentamicin has considerable nephrotoxic effects. Salicylic acid is a phenolic compound that has anti-inflammatory, analgesic and antipyretic effect. It has also antioxidant activity that can counteract oxidative damages induced by adverse conditions in animals. OBJECTIVES: The work aims to detect the harmful changes in the rat kidney that occur after administration of gentamicin and to determine whether salicylic acid treatment attenuates gentamicin - induced nephrotoxicity. MATERIAL AND METHODS: Fifty healthy adult male Wister albino rats were obtained from the breading animal house, Faculty of Veterinary Medicine, Zagazig University. These animals were divided randomly and equally in to five groups. Each group contains ten rats. Group 1: Included control animals. Group 2: Included salicylic acid-treated animals. Group 3: Included gentamicin-treated animals. Group 4: Included animals treated with salicylic and gentamicin at the same time. Group 5: Included animals treated with gentamicin and remain for recovery. The rats were anesthetized with ether inhalation and sacrificed. The kidneys were removed and processed for light and electron microscopic examination. RESULTS: The histological study revealed that gentamicin causes severe nephrotoxicity. Exposure to gentamicin caused necrosis of tubular epithelial cells. The glomeruli were also affected. On the other hand, salicylic acid administration protected kidney tissue against the nephrotoxic effect caused by gentamicin treatment. Recovery from gentamicin treatment could occur spontaneously but it was slow and incomplete. CONCLUSION: Gentamicin administration leads to harmful changes in the structure of the rat kidney. Spontaneous recovery could occur but it is slow and incomplete. These nephrotoxic changes can be protected by co-therapy with salicylic acid
Reham Zakaria Mustafa Mohammed Hamza
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Nephrotoxicity
Elshaymaa Mahmoud Samy Aly Mohamed Morsy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
role of mesenchymal stem cell in treatment of acute nephrotoxicity
Ayesha Abdullah AbuHashim
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Protective roles of thymoquinone and vildagliptin in manganese-induced nephrotoxicity in adult albino rats
Dalia Anas Ibrahim Nasr
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
THE ANTIOXIDANT EFFECT OF GREEN TEA TANNIN ON CISPLATIN- INDUCED NEPHROTOXICITY IN RATS
- Faculty Research Area On Zu Site
THE ANTIOXIDANT EFFECT OF GREEN TEA TANNIN ON CISPLATIN- INDUCED NEPHROTOXICITY IN RATS