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Search Result For 'Pharmacology' , Result Number : 33

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Yasser Abdelaal Sleim Elewa
- Faculty Research Area On Zu Site
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Pharmacology
Hebatallah Husseini Mohamed Atteia
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Pharmacology
Shimaa Samy Mahmoud Othman
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Cardiovascular Pharmacology
Shimaa Samy Mahmoud Othman
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Pharmacology
Sameh Mohamed Mostafa Elnbtete
- Faculty Research Area On Zu Site
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immunopharmacology
Sameh Mohamed Mostafa Elnbtete
- Faculty Research Area On Zu Site
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immuonopharmacology
Sameh Mohamed Mostafa Elnbtete
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pharmacology
Alaa Basuony Ismail Ismaiel
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
42. Alaa Bassuny Ismael, Ayman Abdel-Aziz Swelum, Salama A-H Mostafa and Abdel-Rahman A Alhumiany. Latex agglutination using the periplasmic proteins antigen of Brucella melitensis is a successful, rapid, and specific serodiagnostic test for ovine brucellosis. International Journal of Immunopathology and Pharmacology. 2016, 29 (3), 480-487. DOI: 10.1177/0394632016648709.
Fatma Desouky Mohamed Abdallah
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Evaluation of Immunostimulant Activity of Spirulina platensis (Arthrospira platensis) and Sage (Salvia officinalis) in Nile Tilapia (Oreochromis niloticus) Suhair A. Abdellatief1*, Afaf N. Abdel Rahman2 and Fatma D.M. Abdallah3 1Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, 44511 Zagazig, Sharkia, Egypt 2 Fish Diseases and Management Department, Faculty of Veterinary Medicine, Zagazig University, 44511 Zagazig, Sharkia, Egypt 3Animal Wealth Development Department, Faculty of Veterinary Medicine, Zagazig University, 44511 Zagazig, Sharkia, Egypt Article History: Received: 11/1/2018 Received in revised form: 5/2/2018 Accepted: 15/2/2018 Abstract Immunostimulants have been found to be attractive and promising agents for disease management in aquaculture. The current study aimed to assess the impacts of feeding with Spirulina platensis (SP) and Salvia officinalis (SO) for 28 days on the immune status of Nile tilapia (Oreochromis niloticus). A total of 180 Nile tilapia (30.6 ± 0.12 g) were divided into 3 groups (triplicates of 20 fish/group). Control group was fed on a basal diet only, while the other two groups were supplemented with SP (10 gm/kg diet) and SO (7.5 gm/kg diet) respectively. Both of SP and SO showed in vitro antimicrobial activity against Pseudomonas aeruginosa. The immune response of Nile tilapia supplemented with SP and SO revealed significant increases in lysozyme, nitric oxide activities and IgM titer with enhancement of IL-1β and TNF-α genes expression before and after infection with P. aeruginosa. Fish challenged with P. aeruginosa showed signs of infection with high mortality rate and low relative percentage survival which elevated to be 83% in SP group and 75% in SO group. It could be concluded that dietary supplementation with SP and SO improved immune response and protected Nile tilapia against infection. Moreover, SP showed better results than SO before and after infection.
Ahmed Abdallah Abdulrahman
- Faculty Research Area On Zu Site
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Pharmacology
Ahmed Ezat Mahmoud Mohamed El Zowalaty
- Faculty Research Area On Zu Site
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Molecular Pharmacology and Toxicology
Eman Salah Abdelaziz Souliman
- Faculty Research Area On Zu Site
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pharmacology
Samar Abdelmigeed Mohamed Rezk
- Faculty Research Area On Zu Site
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Cardiovascular Pharmacology
Samar Abdelmigeed Mohamed Rezk
- Faculty Research Area On Zu Site
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Pharmacology
Dalia Mohamed Abdelmoteleb Ali
- Faculty Research Area On Zu Site
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cardiovascular pharmacology
Dalia Mohamed Abdelmoteleb Ali
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
molecular pharmacology
Dalia Mohamed Abdelmoteleb Ali
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
pharmacology of CNS
Dalia Mohamed Abdelmoteleb Ali
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
pharmacology of kidney
Dalia Mohamed Abdelmoteleb Ali
- Faculty Research Area On Zu Site
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pharmacology of liver
Nadya ebasiry Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
International Immunopharmacology 2023; Volume 115: 109621 Background Ulcerative colitis (UC) is a global inflammatory bowel disease. Aime :This study aimed to assess the effects of icosapent ethyl on acetic acid-induced colitis in rats as well as the underlying mechanisms involved. Methods 36 male Wister rats were equally divided into Six groups: control, UC, mesalamine 100 mg/kg, icosapent 150mg/kg, icosapent 300 mg/kg, and EX527-icosapent 300 mg/kg groups. EXcept for control group, UC was induced by acetic acid instillation into colon. Drugs were administered once daily for one week then under thiopental anaesthesia, colons were excised. Colitis macroscopic and microscopic scores were assessed. A part of colon was homogenized for detection of malondialdehyde (MDA), inerleukin1 (IL-1β), tumor necrosis factor (TNF-α), superoxide dis-mutase (SOD), phosphorylated Akt (pAkt) and caspase 3 levels. Silent information regulator 1 (SIRT1), hemeoxygenase 1 (HO-1), and nuclear factor erythroid 2 (Nrf2) mRNA expressions were detected. Mallory-stained colonic sections were examined for collagen fibres detection. Immunohistochemistry of NF-κB and p53 expressions in colonic sections were assessed. Results There acetic acid induced colitis increments in MDA, IL-1β, TNF-α, and caspase 3 levels while decreased SOD, pAkt, SIRT1, HO-1, and Nrf2 with increased collagen fibres as well as NF- κB and p53. Icosapent decreased macro& microscopic colitis scores, MDA, IL-1β, TNF-α, and caspase 3 levels while increased SOD, pAkt, SIRT1, HO-1, and Nrf2 with decreased collagen fibres as well as NF-κB and p53. The effects of icosapent 300 mg/kg were similar to mesalamine. Icosapent effects were antagonized by EX527. Conclusion Icosapent alleviated acetic acid-induced colitis via its anti-inflammatory, Antioxidant, and anti-apoptotic effects mediated in part by SIRT1 pathway activationIcosapent ethyl alleviates acetic acid-induced ulcerative colitis via modulation of SIRT1 signaling pathway in rats
Mohamed Hassan Mohamed Abdel Azeem
- Faculty Research Area On Zu Site
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pharmacology
Nada Ahmed Kamel AbdelMaksoud
- Faculty Research Area On Zu Site
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clincal pharmacology
Mahmoud Hassan Mahmoud Batriq
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Cardiovascular pharmacology
Mahmoud Hassan Mahmoud Batriq
- Faculty Research Area On Zu Site
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Renal pharmacology
Israa Mohamed Fahmy Mohamed Elzaghandy
- Faculty Research Area On Zu Site
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clincal pharmacology
Zeinab Mahmoud Mohammed Ahamed Saeed
- Faculty Research Area On Zu Site
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clinical and experimental pharmacology
Tariq Khamis Kamal Ahmed Khamis
- Faculty Research Area On Zu Site
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molecular pharmacology
zeinab mohamed mamdouh abdelkareem
- Faculty Research Area On Zu Site
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pharmacology
Nasreen Mohammed Ibrahim Moussa
- Faculty Research Area On Zu Site
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pharmacology and toxicology
Nasreen Mohammed Ibrahim Moussa
- Faculty Research Area On Zu Site
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pharmacology of natural neutraceuticals
Maha Sabry El Sayed Kilani
- Faculty Research Area On Zu Site
neuropharmacology
- Faculty Research Area On Zu Site
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pharmacology
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Clinical pharmacology