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ahdab abdou mohamed elmaadawy
- Faculty Research Area On Zu Site
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(( البحث الأول )) الأنواع المختلفة من القهوة لها أثار متنوعه على وزن الجسم ودهون الدم عند فئران التجارب "" الملخص العربى "" مشروب القهوة هو المشروب الأكثر إستهلاكا عالميا ويتم تحضيره بطرق مختلفة. وتهدف هذه الدراسة إلى معرفة آثار الأنواع المختلفة من القهوة على وزن الجسم ونسبة الدهون في الدم في فئران التجارب . تم اجراء الراسة علي أربعون فأرا ألبينو من الذكور وزنهم يتراوح بين 120 – 130 جرام وتم تقسيمهم إلى خمس مجموعات متساوية ( ن = 8 ) , تم إستخدام أنواع مختلفه من القهوة - القهوة التركية متوسطة التحميص ( البن متوسط التحميص ) , والقهوة التركية عالية التحميص ( البن الغامق ) ٬ والقهوة الفورية (النسكاقيه) ٬ والقهوة العربية. تناولت كل مجموعة 2 مل جرعة فموية من أنواع القهوة المختلفة (٠.٠ – ٤.٣- ٤.٣- ١٤.٣ – ٨.٦ ملليجرام / ١٠٠ جرام من وزن الجسم علي التوالي ) . إستمرت التجربة لمدة ٣٠ يوما، ثم تم ذبح الفئران وتجميع عينات الدم وتقدير نسبة الدهون الثلاثية ، الكوليسترول الكلي ، والبروتينات الشحمية عالية الكثافة ٬ والبروتينات الشحمية منخفضة الكثافة والدهون الكلية في مصل الدم . أيضا تم جمع عينات من الكبد ، والكلى ، والقلب لفحص الأنسجة .أظهرت النتائج أن الفئران التي تغذت على أنواع مختلفة من القهوة قد إنخفض وزنها مقارنة بالمجموعة الضابطة . كما أن الفئران التى تغذت على القهوة سريعة الذوبان فقدت كمية كبيرة من وزن الجسم . كان للقهوة التركي عالية التحميص ( البن الغامق ) تأثير معنوي ( مستوي دلالة آقل من ٠.٠٥) فى خفض الدهون الثلاثية في الدم، والكوليسترول ٬ والبروتينات الشحمية منخفضة الكثافة والدهون الكلية ، في حين أنها رفعت تركيز البروتينات الشحمية عالية الكثافة . علاوة على ذلك فإن تغذية مجموعة الفئران على البن القابل للذوبان ( النسكافيه ) قد خفضت نسبة الدهون في الدم . أخيرا فإن تناول كميات معتدلة من القهوة التركي عالية التحميص ( البن الغامق ) لها آثار مرغوبه على نسبة الكولسترول ونسبة الدهون في الدم. الكلمات المفتاحية : قهوه ، الكوليسترول ٬ البروتينات الشحمية ٬ الفئران ٬ وزن الجسم . Different Preparations of Coffee Have Varied Effects on Body Weight and Blood Lipids in Experimental Rats. " Abstract " Coffee beverage is a globally consumed and is prepared in different ways. This study aims at finding out the effects of different preparations of coffee on body weight and blood lipids in experimental rats. Forty male albino rats (130 ± 2.3 g) were divided into five equal groups(n=8), control, Turkish coffee medium roasting (TMC), Turkish coffee dark roasting (TDC), instant coffee (IC), and Arabian coffee (AC). Each group received 2 ml oral dose of coffee (0, 4.3, 4.3, 14.3, 8.6 mg/100 g BW respectively). The experiment continued for 30 days, and by the end, rats were anesthetized and killed for collection of blood samples. Triglycerides, total cholesterol, HDLc, LDLc, VLDLc, and total lipids were determined in serum. Samples of liver, kidney, and heart were collected for histopathological examination. Results showed that rats fed different preparations of coffee had significantly smaller weight gain than control group. On the other hand, group fed instant coffee lost considerable amount of body weight. Among all kinds of studied coffee, the Turkish coffee dark roasting reduced significantly (P<0.05) serum triglycerides, total cholesterol, LDLc, VLDLc, and total lipids, whereas it elevated HDLc concentration. Moreover, group fed Instant coffee showed also lower blood lipids. In conclusion, moderate amounts of Turkish coffee dark roasting have desirable effects on serum total cholesterol, LDLc, and total blood lipids. Keywords: Roasted; Coffee; Cholesterol; LDL; HDL; Rats; Body weight.
Fatma Desouky Mohamed Abdallah
- Faculty Research Area On Zu Site
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AJVS. Vol. 60 (1): 49-54 Jan. 2019 DOI: 10.5455/ajvs.16828 Statistical Approaches for Treatments over Time (Repeated Observations) in Nile Tilapia Fatma D.M. Abdallah Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, 44511Egypt. ABSTRACT Key words: Repeated measure ANOVA, sphericity assumptions, lysozymes, P value and Bonferroni procedure. This study aims to model and analyze repeated observations in some biological sciences and veterinary practices (Nile tilapia fish). Repeated measure ANOVA is used to assess the effect of some treatments over a specific time. Data obtained from an experimental study examining the effect of some immunostimulants (Spirulina platensis (SP) and Salvia officinalis (SO)) on lysozymes activity in Nile tilapia fish which measured repeatedly at two times. The analysis is applied by using the software SPSS version 20 on the data collected at two time points 14th day and 28th day so the correct test was two way repeated measure design. The assumptions of the test were achieved where Huynh-Feldt and Greenhouse-Geisser measures were not significant (P-value > 0.05). The P value for time, treatments and the interaction of them was 0.000, so they have a highly significant effect on the (outcome variable) lysozymes activity of Nile tilapia. Bonferroni correction is used as a post hoc test and its result showed a difference between the groups for each parameter. These results of univariate analysis agreed with the multivariate analysis results.
Fatma Desouky Mohamed Abdallah
- Faculty Research Area On Zu Site
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Evaluation of Immunostimulant Activity of Spirulina platensis (Arthrospira platensis) and Sage (Salvia officinalis) in Nile Tilapia (Oreochromis niloticus) Suhair A. Abdellatief1*, Afaf N. Abdel Rahman2 and Fatma D.M. Abdallah3 1Pharmacology Department, Faculty of Veterinary Medicine, Zagazig University, 44511 Zagazig, Sharkia, Egypt 2 Fish Diseases and Management Department, Faculty of Veterinary Medicine, Zagazig University, 44511 Zagazig, Sharkia, Egypt 3Animal Wealth Development Department, Faculty of Veterinary Medicine, Zagazig University, 44511 Zagazig, Sharkia, Egypt Article History: Received: 11/1/2018 Received in revised form: 5/2/2018 Accepted: 15/2/2018 Abstract Immunostimulants have been found to be attractive and promising agents for disease management in aquaculture. The current study aimed to assess the impacts of feeding with Spirulina platensis (SP) and Salvia officinalis (SO) for 28 days on the immune status of Nile tilapia (Oreochromis niloticus). A total of 180 Nile tilapia (30.6 ± 0.12 g) were divided into 3 groups (triplicates of 20 fish/group). Control group was fed on a basal diet only, while the other two groups were supplemented with SP (10 gm/kg diet) and SO (7.5 gm/kg diet) respectively. Both of SP and SO showed in vitro antimicrobial activity against Pseudomonas aeruginosa. The immune response of Nile tilapia supplemented with SP and SO revealed significant increases in lysozyme, nitric oxide activities and IgM titer with enhancement of IL-1β and TNF-α genes expression before and after infection with P. aeruginosa. Fish challenged with P. aeruginosa showed signs of infection with high mortality rate and low relative percentage survival which elevated to be 83% in SP group and 75% in SO group. It could be concluded that dietary supplementation with SP and SO improved immune response and protected Nile tilapia against infection. Moreover, SP showed better results than SO before and after infection.
Fatma Desouky Mohamed Abdallah
- Faculty Research Area On Zu Site
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Zagazig Veterinary Journal, ©Faculty of Veterinay Medicine, Zagazig University, 44511, Egypt. Volume 47, Number 2, p. XXX, June 2019 DOI: 10.21608/zvjz.2019.11121.1034 RSEARCH ARTICLE Application of Different Biostatistical Methods in Biological Data Analysis Khairy M. El-Bayomi, Fatma D. Mohamed, Mahmoud S. El-Tarabany and Hagar F. Gouda* Animal Wealth Development Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt Abstract Logistic regression is one of the popular methods used in genetic data analysis. That is applied to predict a categorical binary dependent variable on basis of predictor variables, and to test the probability of getting a particular value of the dependent variable that is related to the explanatory variable. The objective of this study is to highlight the crucial role of biostatistical methods in increasing the accuracy of the results in veterinary and biological practices. Statistical analysis of previously published data in the National Research Center, Dokki, Giza, Cairo, Egypt was done using SPSS version, 24 to predict hepatocellular carcinoma metastasis by knowing the genotypes, age, and gender of the patients. The genotypes and gender displayed a significant effect on metastasis (P < 0.05) while age had no significant effect on metastasis (P > 0.05). There are other types of data (animal breeding and production) which were analyzed by repeated measures ANOVA and principal component analysis (PCA). The repeated measures ANOVA is equivalent to normalized ANOVA, but for related, not independent groups. Data of this test was obtained from a study aimed to measure body weight of three breeds of rabbits at 4 time points 4th, 6th, 8th and 10th weeks of the experiment. The main effect of breed types of rabbits was significant (P < 0.05), the time (weeks) was highly significant (P < 0.001) and their interaction was also highly significant (P < 0.001). Principal component analysis (PCA) is used to reduce a large set of variables to a small set that still contains most of the information in the large set. A reduced set is easier to analyze and interpret. Data with 6 variables reduced to only 2 variables where initial eigenvalues were > 1 for two variables and their values were (2.768 and 1.147).
Wafaa Mohamed Ismail Elhag
- Faculty Research Area On Zu Site
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Comparative study for diagnosis of babesiosis and theileriosis in different age groups of cattle in some localities in Egypt with treatment trials
Walid Rezk Alghareeb Elsaied
- Faculty Research Area On Zu Site
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THE EFFECT OF ROSEMARY EXTRACT AND LACTIC ACID ON THE QUALITY OF REFRIGERATED BROILER FILLETS Mohamed A. Hussein1, Waleed R. El-Ghareeb1,2 and Mohammed A. F. Nasr3 1 Department of Food Control, Faculty of Veterinary Medicine, Zagazig University, Egypt. 2 Department of Veterinary Public Health and Animal Husbandry, College of Veterinary Medicine, King Faisal University, Saudi Arabia. 3 Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, Egypt. Abstract The current study investigated the effect of rosemary extract (0.2% RE) and lactic acid (1% LA) on some freshness, bacterial parameters and formation of biogenic amines during refrigeration of broiler fillets. Ninety broiler fillet samples were divided into three groups (each 30). The control group was dipped in sterile distilled water, while the RE and LA groups were dipped in rosemary extract 0.2% (w/v) and lactic acid 1% (w/v), respectively. Sensory evaluation, pH, total volatile basic nitrogen (TVB-N), thiobarbituric acid reactive substances (TBARS), total psychrotrophic and Enterobacteriaceae counts were performed at zero time and at 3 days interval until the group were rejected from sensory analysis. Organoleptic scores were unacceptable after the 9th, 12th and 15th day of refrigeration in control, RE and LA groups, respectively. TVB-N was the lowest in LA group (3rd day; 4.36 ± 0.12, 6th day; 5.62 ± 0.7 and 9th day; 10.13 ± 0.98) when compared with the RE and control groups. Moreover, TBARS was the highest in the control group (3rd day; 0.22 ± 0.06, 6th day; 0.39 ± 0.07 and 9th day; 0.78 ± 0.09) when compared with the RE and LA groups. LA group showed the lowest number of psychrotrophic bacteria during refrigeration period when compared with the other groups. Enterbacteriaceae was detected at zero, 3rd and 6th day in control, RE and LA groups, respectively. This study concluded that dipping in LA 1% or RE 0.2% reduce the psychrotrophic and Enterobacteriaceae bacteria of broiler fillet and increased the acceptability of refrigerated fillet, decreased the biogenic amines formation and rancidity. Therefore, broiler fillets dipped in RE 0.2% or LA 1% can be used up to 12 or 15 days when refrigerated at 4°c C. مكان النشر: Journal of Food Science and Technology; 55 (12): 5025–5034 (2018).
Doaa Mohamed Kamel Bayomy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
effect of a proposed program on self-confidence, frequency Skill performance for and some variables crawling on the back The research aimed to identify the use of the design of a program (psychological - educational) to develop self-confidence and reduce the level of psychological frequency and teach swimming crawl on the back, The researchers used the experimental method on a sample of (40) students for the second year students of the Faculty of Physical Education Girls Zagazig University were divided into two groups, one experimental and the other control of the strength of each (20) students. Research tools include: Skill tests - Psychometrics - Physical tests - Educational program The researcher used the following statistical methods: arithmetic mean - standard deviation - median - torsion coefficient - Test "T" - correlation coefficient - improvement rates%. The most important results are: - Psychological-educational program proposed by the two researchers is more influential and positive than the traditional method of developing self-confidence and reducing the level of psychological hesitation of students. - The psychological and educational program proposed by the two researchers is more influential and positive than the traditional method of learning the skills of swimming crawling backpacks for students. One of the main recommendations: - The use of the program (psychological - educational) proposed that was applied in this research in swimming lectures. - To pay attention to the psychological aspects of practitioners of various sports activities in all stages of the age and the use of sports practice in the development of their psychological skills
Doaa Mohamed Kamel Bayomy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Effect of using the Dalton method supported by M-learning Learn to swim chest The researcher used the experimental method on a sample of (40) students of the second year students of the Faculty of Physical Education Girls Zagazig University were divided into two groups, one experimental and the other control officer each (20). Students. Research tools include: Skill Tests - Cognitive Achievement Test - Educational Program. The researcher used the following statistical methods: - Arithmetic mean – standard deviation – median – torsion coefficient – T – test – correlation coefficient – improvement rates%. The most important results are: 1- The experimental group that used the Dalton method supported by mobile learning (M-Learning) over the control group that used the traditional method (verbal explanation and performance of the practical model), which shows its effectiveness and its effect on learning chest swimming. 2- Dalton method supported by mobile learning to take into account the differences between the individual students. Key recommendations include: 1- Using the Dalton method supported by mobile learning with other swimming methods and other sports activities. 2- The need to hold training courses for those teaching swimming, in order to identify the latest educational methods. 3- Attention to the teaching of cognitive content beside the skill content of swimming, which helps to expand the learner's perceptions, which facilitates the learning process.
Doaa Mohamed Kamel Bayomy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The effect of an integrated E-learning program on learning motivation and cognitive achievement to swim crawling The researcher used the experimental method on a sample of (30) female students of the first division of the Faculty of Physical Education Girls Zagazig University were divided into two groups, one experimental and the other a female officer each Of them (15) students. Research tools include: skills tests, cognitive achievement, test in the educational program using the educational software. The researcher used the following statistical methods: arithmetical mean - standard deviation - median - torsion coefficient - T test - coefficient of correlation - improvement rates%. The most important results are: 1. The experimental group using the integrated learning mode (e-learning - traditional education) is superior to the control group that used the traditional method (verbal explanation and practical model performance), which indicates the effectiveness of the combined learning and its impact on learning the skills of the crawling swimmer on the abdomen. 2. Integrated e-learning is more effective than instruction learning by improving the level of performance of the abdominal crawling pool (under research), cognitive achievement and increasing motivation towards learning among students. One of the main recommendations: 1- The necessity of using the integrated e-learning strategy in teaching swimming. 2- The use of technology in education to increase the motivation of learning among students. 3- Develop programs to develop the motivation of learning among students, which leads to faster learning and improve the level of skilled performance.
Doaa Mohamed Kamel Bayomy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The Effect of Using Differentiated education On the achievement of knowledge and skills of the first star in the signature swimming The researcher used the experimental method on a sample of (40) female students of the Fourth division of the Faculty of Physical Education Girls Zagazig University were divided into two groups, one experimental and the other a female officer each Of them (20) students. Research tools include: skills tests - cognitive achievement - test in the educational program. The researcher used the following statistical methods: arithmetical mean - standard deviation - median - torsion coefficient - T test - coefficient of correlation - improvement rates%. The most important results are: 1- The use of differential education has a positive effect on the cognitive achievement and level of performance of the first star skills in the signature swimming pool (under consideration). 2- Differentiated education is more effective than the method of learning by orders in the achievement of knowledge and improve the level of performance of the skills of the first star in the swimming signature (under consideration). One of the main recommendations: 1- The need to use a distinctive education as one of the modern teaching methods to learn and master the cognitive and motor aspects in the swimming signature. 2- The importance of the introduction of teaching methods that give an effective role to the student during the educational process in line with the modernization and educational development, including the teaching method distinct 3- Conduct similar studies using the differentiated education and learn about its impact on other water sports.
Doaa Mohamed Kamel Bayomy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The effectiveness of the objective exercises on the level of start-up and rotation performance In swimming crawling The researcher used the experimental method on a sample of (30) female students of the third division of the Faculty of Physical Education Girls Zagazig University were divided into two groups, one experimental and the other a female officer each Of them (15) students. Research tools include: skills tests, Physical tests, educational program. The researcher used the following statistical methods: arithmetical mean - standard deviation - median - torsion coefficient - T test - coefficient of correlation - improvement rates%. The most important results are: 1. The experimental group that used the objective exercises outweighed the control group which used the traditional method (verbal explanation and performance of the practical model), which indicates its effectiveness and its effect on learning to start and circulation in swimming crawling on the abdomen. 2. The use of objective exercises has a positive impact on the level of performance and the start time and rotation in swimming crawling on the abdomen. One of the main recommendations: 1- The use of objective exercises in education because of its effectiveness in improving the level of performance and the start time and rotation in swimming crawling on the abdomen for students of the third year at the Faculty of Physical Education Girls Zagazig University. 2- The need to instruct faculty members and those who teach swimming methods to include educational programs on the purpose exercises, in order to avoid the rigidity of the traditional method of teaching.
Doaa Mohamed Kamel Bayomy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The effectiveness of the use of electronic maps strategy concepts to learn some skills Basic and cognitive achievement in water polo Research was to identify the effect of using electronic maps strategy concepts on the collection of knowledge and learn some of the basic skills in water polo, the researcher used the experimental method on a sample of (30) student fourth year specialization pool Faculty of Physical Education Girls Zagazig University, has been divided into two groups: an experimental one and the other officer strength each of them (15) students. Research tools: Tests skill - Test cognitive achievement in water polo - general mental ability test "intelligence" - electronic maps strategy concepts. The researcher used the following statistical methods: Al_husaby- average standard deviation - the mediator - convolution coefficient - Test "T" - the correlation coefficient -% improvement ratios. Important results: 1. The use of teaching of electronic maps strategy concepts positive impact on the learning some the basic skills (standing in deep water - caught and catch the ball - crawl swimming in water polo - swimming ball - pass the ball - straighten the ball) and cognitive achievement in water polo. 2. Electronic maps strategy concepts the more effective than learning commands in improving the performance of some of the basic skills (under discussion) and cognitive achievement in water polo. One of the main recommendations: 1. Use the electronic maps strategy concepts in the teatching of basic skills in the water polo. 2. Inclusion strategies concept maps within the decisions of teatching methods of Water Sports Faculty of Physical Education.
Nadia Hassan Elsayed Zaghlol
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"The effect of a virtual reality program on the level of the professional competencies of the student teacher in the Faculty of Physical Education, Zagazig University" Prof. Nadia Hassan Zaghloul The research aims to identify the effectiveness of a virtual reality style at the level of the professional requirements of the student teacher in the Faculty of Physical Education, Zagazig University. The researcher used the experimental approach, and the experimental design was used for two groups, one experimental and the other is controlled by following the pre and post measurement for each of them. The sample of the research is on (70) female students who were chosen intentionally from the members of the research community. (40) female students were extracted to conduct the basic study of the research. The results resulted in: 1- The educational program using virtual reality technology has a positive impact D in the development of the professional competencies of the student teacher under discussion. 2- The method used to teach physical education classes in schools while performing illustrative models of motor performance from the teacher, which has a positive effect on the development of professional competencies of the control group. 3 - The method of learning with virtual reality technology led to an improvement in the level of professional competencies of the student student compared to the method based on the performance of the model within the class.
Nadia Hassan Elsayed Zaghlol
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"The effectiveness of the inverted classroom strategy on the level of learning some basic gymnastics skills for female students in the fifth grade of education The main country in the United Arab Emirates " Prof. Nadia Hassan Zaghloul The research aims to identify the effectiveness of the inverted class strategy at the level of learning some basic skills in gymnastics for female students of the fifth grade of basic education in the United Arab Emirates. The research community included students of the fifth grade in the first stage of basic education in the UAE and those affiliated with the Palm School for the academic year (2015/2016), whose number is (100) pupils for the academic year (2014-2015 AD). The research sample was chosen in the random, deliberate way for (66) pupils From the research community, they were divided into two groups, one is experimental and the other is a strength of each (25) students. Harmonization was carried out between the research group. the test T for measuring physical capacity, the proposed tutorial using an inverted grade strategy. The results resulted in: 1. The proposed program using the inverted class strategy contributed positively to the development of motor skills on the ground movement apparatus in gymnastics among female pupils of the first stage of basic education. 2. The traditional method positively contributed to the development of motor skills on the ground movement apparatus in gymnastics for pupils of the first stage of basic education. 3. The inverted classroom learning program has a more positive effect than the proposed traditional program on developing motor skills on the device of ground movements in gymnastics for pupils of the first stage of basic education
Nadia Hassan Elsayed Zaghlol
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The effect of using a curriculum for kinetic stories, physical education lesson to modify the social adjustment of first-grade students In the United Arab Emirates Prof. Nadia Hassan Zaghloul Dr. Hisham Ismail Hilal The research aims to build a curriculum for kinetic stories to provide students with social adjustment through the proposed kinematic curriculum, and to identify the differences between the two dimensional measurements of the experimental and control groups in the level of social adaptation in the research sample and to identify the differences between the two dimensional measurements of the experimental and control groups in the level of social adjustment in a sample The research, and the researchers used the descriptive approach (survey method) to develop the methodology of the motor story in addition to the experimental approach in designing the experimental and control groups, due to its suitability of the nature of the research. The research community included those enrolled in the first grade of primary school for the academic year (2012/2013) at Al-Nakheel School for Basic Education H1 (primary) girls in the Emirate of Ras Al-Khaimah (in the Emirates) in which the first researcher works. One of the data collection tools is the analysis of references, personal interviews, questionnaire forms. The results resulted in: 1. The proposed curriculum of the kinetic story has a positive effect on the social adjustment of female students. 2. The curriculum followed has a positive effect on the social adjustment of female students. 3. The proposed kinetic curriculum has a better positive effect than the curriculum used for first-grade students in the primary stage in the United Arab Emirates
Nadia Hassan Elsayed Zaghlol
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The effect of using the "Jixu" strategy for cooperative learning and purpose games on learning the long jump for prep sports pupils Prof. Nadia Hassan Zaghloul The research aims to design a proposed educational program using the "Jixu" strategy for cooperative learning and purpose games, and to identify the digital achievement and level of technical performance of long jump and cognitive achievement among students under research, and the researcher used the experimental approach using the experimental design of two groups, one is experimental and the other is control, by following measurements Tribal and postgraduate, due to its suitability of the nature of this study, the research community includes all students of the first preparatory class in the preparatory sports school for girls in the city of Zagazig in Sharkia Governorate, the Western Educational Administration, which number (38) It has a strength of two classes registered in the academic year 2018/2019, and (5) female students were withdrawn as a sample for the exploratory study to find scientific transactions and take tests, and (3) female students with certificates of injuries were prevented from participating, thus the basic sample (30) students were divided into two equal groups The first is experimental and the second is a control group consisting of (15) students each. Data collection tools include measurements of the growth rate, physical and cognitive tests for long jump. The results resulted in: 1. There are statistically significant differences and the rate of accident change between the averages of the pre and post measurements of the experimental group in the physical tests and the digital carp, and the evaluation of the technical performance level of the long jump, and the cognitive achievement under investigation and in favor of the dimensional measurement. 2. There are statistically significant differences and the rate of accident change between the averages of the pre and post measurements of the control group in physical tests, numerical achievement and assessment of the level of technical performance of the long jump and the cognitive achievement under investigation and in favor of the dimensional measurement. 3. There are statistically significant differences and the rate of accident change between the averages of the dimensional measurements of the experimental and control groups, in favor of the dimensional measurements of the experimental group in the physical variables and numerical achievement and assessing the level of technical performance of the long jump and knowledge achievement under investigation.
Khaled Mohammed Ali AlMarakby
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Effect of lunar cycle on some reproductive aspects of female goats. Abdel-Halim A. El-Darawanya, Mahmoud S.El-Tarabanyb,Khaled M. Al-Marakbya, and Mostafa A. Attac a Department of Animal production, Faculty of Agriculture, Zagazig University, Sharkia,Egypt. b Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Egypt. c Biological Applications Department, Radioisotopes Applications Division, NRC, Atomic Energy Authority, Inshas, Sharkia, Egypt. Abstract The aim was to evaluate the possible effects of different lunar phases at birth on the pre-pubertal changes in the body measurements, blood parameters and hormonal profile of female goats. Based on the birth date, 36 female Nubian kids (3 months of age) were selected to equally represent the new (NL), full (FL) and old (OL) phases of the lunar cycle. Female goats in the FL group showed significantly higher body weights at weeks 20, 24 and 28 of age compared to the OL group (P = 0.050, 0.033 and 0.046,respectively). Female goats in the FL group exhibited estrus signs earlier than those in the OL group (P = 0.013). At the age of puberty, the values of Spinnbarkeit and ferning arborization of cervical mucus in the FL group were significantly greater than the NL and OL groups (P = 0.001 and 0.040, respectively). At weeks 26 and 27 of age, female goats in the FL group had significantly greater serum progesterone (P = 0.006 and 0.001, respectively) than did the NL and OL groups. In conclusion, the FL group reached the puberty at an early age and exhibited higher cyclic progesterone levels than did the NL and OL groups.
Khaled Mohammed Ali AlMarakby
- Faculty Research Area On Zu Site
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Effect of synchronization protocols on reproductive indices, progesterone profile and fertility under subtropical environmental conditions in repeat breeder Holstein cows. Mahmoud S. El-Tarabany a and Khaled M. Al-Marakby b a Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Egypt. b Department of Animal production, Faculty of Agriculture, Zagazig University, Sharkia,Egypt. Abstract The objectives were to evaluate the reproductive indices and survival analysis of pregnancy outcomes in multiparous repeat breeder Holstein cows (n = 557). The cows were synchronized to ovulate by Ovsynch, new controlled internal drug release device (N-CIDRsynch), and once-used CIDR device (U-CIDRsynch). The pregnancy per AI at 28 days post-insemination (P/AI 28) in the N-CIDRsynch group (28.75%) was significantly (COR = 1.49; p = 0.011) greater than that reported in the Ovsynch (23.46%) and U-CIDRsynch (21.73%) groups. Furthermore, the pregnancy per AI at day 75 post-insemination (P/AI 75) in the N-CIDRsynch group was significantly greater than the Ovysync group (COR = 1.35; p = 0.050). The repeat breeder cows received a N-CIDR device had a significantly higher progesterone level on day 2 and day 4 of CIDR insertion (1.38 and 1.67 ng/ml, respectively) than those received a U-CIDR device or the control group (p = 0.012 and 0.001, respectively). The Cox regression model recorded significant associations for synchronization protocols, THI at the TAI and season of calving with the hazard of P/AI 28 and P/AI 75 (p = 0.044 and 0.046; 0.001 and 0.005; 0.003 and 0.001, respectively). Multiparous repeat breeder cows (>3) had a lower hazard ratio (HR) of P/AI 28 than that reported in the reference (2nd parity) group (HR = 0.74, p = 0.050). The repeat breeder cows inseminated at 76–80 and >80 temperature-humidity index (THI) had significantly lower HR of P/AI 28 than those inseminated at the baseline (<70) THI value (HR = 0.73 and 0.30, p = 0.036 and 0.001, respectively). The current results indicate that the use of N-CIDR synch protocol may achieve satisfactory pregnancy outcomes in repeat breeder cows.
Khaled Mohammed Ali AlMarakby
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
0.05) effects on final body weight, total body weight gain, feed input, feed conversion ratio, relative growth rate and protein productive value. The findings of blood hematological and biochemical parameters did not significantly differed among the experimental groups (P > 0.05). The mortality rate was considerably decreased in the T5 group when compared with the control group. The parameters of health conditions were homogeneous in all dietary groups. The relative profit was significantly increased with all inclusion levels of DDGS compared with the control diet (T1). In conclusion, incorporation of DDGS instead of the mixture of fish meal, soybean meal and yellow corn up to the level 30 % had no negative effects on productive performance, and health condition, with a considerable improvement in the economic efficiency of Nile tilapia fish diets.'>Impact of distiller's dried grains with solubles on health and performance of Nile tilapia (Oreochromis niloticus) fish. Mohamed Mostafa Khadr 1, Khaled M. Al-Marakby 2, Sabry, A. Shehata 2 and Mohamed S. Ebrahim 1 1 Central Laboratory of Aquaculture Research, Abbasa, Abo-Hammad, Sharkia, Egypt. 2 Animal Production Department, Faculty of Agriculture, Zagazig University, Egypt. Abstract This work was conducted to study the impact of dried distiller grain with solubles (DDGS) incorporation in Nile tilapia (Oreochromis niloticus) diets on performance, health and economic efficiency. An aggregate number of 200 Nile tilapia fingerlings (Average body weight 12.86 g ± 0.14) were randomly distributed into five experimental groups, with 4 replicates (Glass aquaria) contain 10 fingerlings per each. Five diets were formulated to contain 0 (Control diet based on fish meal, soybean meal and yellow corn), 5, 10, 20 and 30% DDGS (T1, T2, T3, T4 and T5 , respectively). The fingerlings received the experimental diets twice daily to apparent satiation for 16 weeks. All inclusion levels of DDGS (5, 10, 20 and 30%) had no significant (P > 0.05) effects on final body weight, total body weight gain, feed input, feed conversion ratio, relative growth rate and protein productive value. The findings of blood hematological and biochemical parameters did not significantly differed among the experimental groups (P > 0.05). The mortality rate was considerably decreased in the T5 group when compared with the control group. The parameters of health conditions were homogeneous in all dietary groups. The relative profit was significantly increased with all inclusion levels of DDGS compared with the control diet (T1). In conclusion, incorporation of DDGS instead of the mixture of fish meal, soybean meal and yellow corn up to the level 30 % had no negative effects on productive performance, and health condition, with a considerable improvement in the economic efficiency of Nile tilapia fish diets.
Khaled Mohammed Ali AlMarakby
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Impact of lunar phase at birth on testicular morphology, semen characteristics and blood chemistry of male goats. Mahmoud S. El-Tarabany a, Abdel-Halim A. El-Darawany b, Akram A. El-Tarabany c and Khaled M. Al-Marakby b a Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Egypt. b Department of Animal production, Faculty of Agriculture, Zagazig University, Sharkia,Egypt. c Biological Applications Department, Radioisotopes Applications Division, NRC, Atomic Energy Authority, Inshas, Sharkia, Egypt. Abstract The aim was to investigate the possible effects of different lunar phases at birth on the pre-pubertal changes in the body weights, blood parameters and hormonal profile of male goats. Based on the birth date, 33 male Nubian kids (3 months of age) were selected to represent the new (NL), full (FL) and old (OL) phases of the lunar cycle. The FL group exhibited the signs of puberty earlier than the NL and OL groups (P=0.011). At the age of puberty, bucks in the FL group had significantly higher ejaculate volume (P=0.010), sperm cell concentration (P=0.004), mass motility (P=0.016) and the percentage of live spermatozoa (P=0.008) as compared to the NL and OL groups. Additionally, male goats in the FL group showed significantly higher serum testosterone levels at week 25, 26, 27 and 28 of age compared with the NL and OL groups (P=0.002, 0.013, 0.038 and 0.004, respectively). In conclusion, the growing males in the FL group reached the puberty earlier than the NL and OL groups. Moreover, this study may help to maximize the semen quality and develop more effective AI strategies in the modern goat production systems.
Khaled Mohammed Ali AlMarakby
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Induction of ovulation in liza ramada (RISSO, 1826) out of season. Mohamed A. Naiel, Abdel-Halim A. El-Darawany, Abdel-Mageed E. Nasr, and Khaled M. Al-Marakby. a Department of Animal production, Faculty of Agriculture, Zagazig University, Sharkia,Egypt. Abstract The present work was designed to determine the suitable hormonal requirements for induction of ovulation in the thin-lipped grey mullet (Liza ramada) reared in brackish water earthen pond out of season. At April 2014, eight groups of grey mullet (6 females / group) were collected and kept in aquaculture pond. The first group (G1) did not receive the hormonal treatment. The mullets of the other seven groups were subjected to intramuscular injection of hormones as follows: G2, 4500 IU/Kg human chorionic gonadotropin (hCG); G3, 3 mg melatonin (ML) /fish; G4, 3 carp pituitary extract (cPE) / fish; G5, a combination of 4500 IU/Kg hCG + 3 cPE / fish; G6, a combination of 4500 IU/Kg hCG + 3mg/ ML fish; G7 , a combination of 4500 IU/Kg hCG + 3 adrenal gland (AD) / fish; G8, a combination of 3 cPE + 3mg/ ML fish. The results after 24hr of injection revealed that estradiol 17-β (E2) level in the collected serum experimental mullets was increased (P < 0.05) with G2 treatment. In the same trend, gonadosomatic index (GSI) was significantly (P < 0.05) increased with G2. The serum Progesterone (P) concentration and Progesterone/Estradiol 17-β ratio (P/E2) were significantly (P < 0.05) increased with G5 than other groups. The G5 group showed oocytes maturation and ovulation superior to that of all other groups, with ripped oocyte and other different maturity stages in Liza ramada out of season. It could be concluded that, 4500 IU/kg of hCG and 3 cPE combination had successfully induced the oocyte maturation in Liza ramada fish reared in brackish water under captivity out of season and a higher dose would induce the ovulation and spawning.
Jasser Ali Ali Abdelmoaty
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Abstract Background: Adequate pain control after cardiac surgery is essential. Paravertebral block is a simple technique and avoids the potential complications of epidural catheters. The objective of this study is to compare the effect of ultrasound-guided bilateral thoracic paravertebral block with thoracic epidural block on pain control after cardiac surgery. Materials and methods: Between March 2016 and 2017, 145 patients who had cardiac surgery through median sternotomy were randomized by stratified blocked randomization into two groups. Group I (n = 70 patients) had bilateral ultrasound-guided thoracic paravertebral block and Group II (n = 75 patients) had thoracic epidural analgesia. The primary end point was the postoperative visual analogue scale (VAS). The duration of mechanical ventilation, intensive care unit (ICU), and hospital stay were the secondary end points. The study design is a randomized parallel superiority clinical trial. Results: Both groups had similar preoperative and operative characteristics. No significant difference in VAS measured immediately after endotracheal extubation then after 12, 24, and 48 hours between groups (p = 0.45). Pain score significantly declined with the repeated measures (p < 0.001) and the decline was not related to the treatment group. Postoperative pain was significantly related to diabetes mellitus (p = 0.039). Six patients in group I (8.5%) required an additional dose of morphine versus three patients (4%) in group II (p = 0.30). Patients in group I had significantly shorter ICU stay (p = 0.005) and lower incidence of urinary retention (p = 0.04) and vomiting (p = 0.018). No difference was found in operative complications between groups. Conclusion: This randomized parallel controlled trial demonstrates that ultrasound-guided paravertebral block is safe and effective method for relieving post-cardiac surgery sternotomy pain compared with thoracic epidural analgesia but not superior to it.
Jasser Ali Ali Abdelmoaty
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
ABSTRACT Background: Pleural drainage is the preferred treatment for patients with symptomatic malignant pleural effusion. Insertion of a large bore chest tube for drainage prior to chemical pleurodesis is a standard treatment procedure. Small sized catheters (pigtail) are another option. However, for use in pleural drainage and pleurodesis, the optimal size of chest drains is still debatable. The aim of the study: Comparing the consequences and efficacy of bleomycin in pleurodesis using small sized pigtail (10-12 Fr) versus chest tube (24-30 Fr) in malignant pleural effusion. Patients and methods: A total of 130 patients with malignant pleural effusion were enrolled in this study. The patients were divided into two categories, Group A: a small sized pigtail catheter (10-12 French) was used in 72 patients and group B: a chest tube (24-30 French) was used in 58 patients. Male patients were 19 in group A and 18 in group B, with nearly same age range (51-67) and (55-70) year, respectively. All patients with manifested coagulopathy, loculated effusion or serious comorbidity were excluded. Results: Comparative results found that lung cancer was the main cause in both groups: adenocarcinoma 38.9 % in group A and 37.9 % in group B, followed by squamous cell carcinoma 11.1 % versus 6.9 %, respectively. Most body cancers were presented in both groups except stomach cancer was 0 % in both groups. Total success was slightly higher in group A 75 % compared to 72.4 % in group B but not statistically significant. Total hospital stay, postoperative pain score and dyspnea incidence were significantly less in group A where small pigtails were inserted. Conclusion: The chemical pleurodesis with bleomycin using small pore catheter (Pigtail) in MPE management is more effective, more patient- tolerable, than chest tube method. It is recommended to use of the pigtail drainage system rather than a chest tube in the treatment of MPE.
Jasser Ali Ali Abdelmoaty
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Abstract Background: There are different techniques for thoracoscopic sympathectomy for management of primary hyperhidrosis. Each technique has the advantage of giving good surgical results, but may cause complications, which depend on the level of sympathectomy used in each technique. Methods: From October 2012 to August 2016, a total number of 120 patients (of primary palmar and axillary hyperhidrosis) were enrolled in this prospective randomized study. Patients were randomized preoperatively and divided into 2 groups: group A (underwent T2, T3, and T4 sympathectomy) and group B (underwent T3 and T4 sympathectomy) with 1 year of follow-up. Improvement of palm sweating, development of complications, patient satisfaction, and quality of life were evaluated. Results: Family history was positive in 33 patients (55%) in group A and in 31 patients (52%) in group B. All patients had improvement of hand sweating. Overdry hands were significant in group A (p = 0.032). Compensatory sweating was significant in group A after the first month (p = 0.016), after 6 months (p = 0.022), and after 12 months (p = 0.025). In group B, very satisfied patients were significant after 6 and 12 months (p = 0.002 and 0.000, respectively). Conclusions: Limited sympathectomy to the level of T3 and T4 has the same therapeutic effect obtained by T2, T3, and T4 sympathectomy with less complications, greater patient satisfaction, and better quality of life. It should be the technique of choice for treatment of primary palmar and axillary hyperhidrosis.
Jasser Ali Ali Abdelmoaty
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
ABSTRACT This study aims to compare the effectiveness of endotracheal intubation with mechanical ventilation and noninvasive ventilation as the most in common methods used in management of ICU chest trauma patients. Sixty-eight patients with chest trauma aged 20–70 years were participated in this study for 2 years. The patients attended to cardiothoracic surgery department, Zagazig University Hospital. The Patients enrolled in this study were divided into 2 groups: the first one received endotracheal intubation with mechanical ventilation (MV group) (Group 1, n = 34) and the other received noninvasive ventilation (NV group) (Group 2, n = 34). All enrolled patients were monitored with clinical criteria including RR, HR, MAP and SpO2. The software SPSS was used for the statistical analysis. P value < 0.05 was considered as statistically significant. The present study resulted that the mean HH, HR, pO2, pCO2 and P/F ratio were improved in the MV group as well as in the NV group but this improvement was not significant. The use of noninvasive ventilation reduces mortality, damages, and complications as well as the length of stay in intensive care (ICU), which leads to low cost.
Hatem Mohamed Elsayed Hussien
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
nutritional assessment of special groups
Nadya ebasiry Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
ABSTRACT Background: Chromium is generated as a waste product from different industries. Its reproductive toxicity has been addressed in many studies that considered oxidative stress the main contributing factor for such toxicity. Selenium is essential for male reproductive health and crucially involved in regulation of cellular redox status. Aim: To elucidate the potential impacts of potassium dichromate (PDC) on the structure of the epididymis, prostate and seminal vesicles and to investigate the efficacy of selenium on counteracting these impacts. Methods: Thirty-six adult male rats were assigned into four groups: control, selenium, PDC, and PDC+selenium. The animals were subjected for a treatment period of four weeks. At the end of experimental period, blood and semen samples, epididymides, prostates and seminal vesicles were collected and processed for biochemical, morphological and immunohistochemical analyses. Results: PDC administration significantly deteriorated sperm parameters and triggered alteration of cellular redox homeostasis, evidenced by increased serum malonaldehyde levels with decreased enzymatic activity of the antioxidants: superoxide dismutase and catalase. Furthermore, PDC significantly unregulated the expression of the serum inflammatory markers; nuclear factor-kappa B (NF-κB), tumor necrosis factor alpha and interleuken-1beta. Microscopically, all the examined tissues of PDC-treated rats displayed deteriorated microarchitecture as well as elevated 8-hydroxy-2-deoxyguanosine and microtubuleassociated protein light chain3 immunoexpression, indicating increased oxidative DNA damage and autophagy activity. Selenium supplements to PDC-treated rats effectively alleviated all the tested parameters. Conclusion: Selenium supplements could effectively mitigate PDC-induced damage of the epididymis, prostate and seminal vesicles through counteracting oxidative stress, and reducing NF-κB activation and excessive autophagy evoked by PDCSELENIUM COULD ALLEVIATE POTASSIUM DICHROMATE-INDUCED EPIDIDYMAL, PROSTATIC AND SEMINAL VESICLE CHANGES IN ADULT RATS: POTENTIAL ROLE OF INHIBITING NF-ΚB PATHWAY
Nadya ebasiry Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
ABSTRACT Background: Hyperglycemia associated with the diabetes mellitus (DM) commonly results in structural abnormalities and hyposalivation in the parotid glands. An antioxidant action in a potent multivitamin called Antox (ANX) aids in reducing oxidative stress. Aim of study: The current study examined the role of ANX in preventing complications from diabetes in the parotid gland, as well as its potential mechanisms. Material and methods: 36 rats were randomly divided into six groups; each group contained six rats. Group 1 (Negative (-ve) control): the rats received only regular food and water. Group 2 (vehicle group): rats received a single i.p. dose of citrate buffer as a vehicle. Group 3: rats were given ANX by oral gavage with a polyethylene canula 0.5 mm in a volume not to exceed 0.3 ml/100 gm at a dose of 10 mg/kg/day. Group 4 (Diabetic/ DM): rats received a single i.p. dose of 50 mg/kg of STZ dissolved in citrate buffer. Group 5 (DM+ Insulin): rats received a single i.p. dose of 50 mg/kg of STZ dissolved in citrate buffer and insulin (Mixtard 30/70; Novo Nordisk) 1 U/100 gm once daily subcutaneous (S.C.). Group 6 (DM+ Insulin + ANX): rats received a single i.p. dose of 50 mg/kg of STZ and insulin 1 U/100 gm /day/S.C. then received ANX orally in a dose of 10 mg/kg/day. All medications were given for 4 weeks. Rats were anaesthetized, and the parotid tissues were obtained for biochemical analysis to measure Malondialdehyde (MDA), superoxide dismutase (SOD), reduced glutathione (GSH), and nitric oxide (NO), for Histopathological examination (Hematoxylin and Eosin staining, Masson trichrome stain) and immunohistochemistry using (8-OHdG, α-SMA and BAX). Results: Remarkably, co-administration of ANX with insulin significantly reduced malondialdehyde (MDA) levels and increased expression of 8-hydroxy-2'-deoxyguanosine (8-OHdG) while enhancing the activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), and total antioxidant capacity (TAC). Additionally, compared to the diabetic rat group and the diabetic group receiving insulin, the combination of ANX and insulin resulted in a considerably decreased expression of Bcl-2, Associated X-protein (Bax) and Smooth muscle alphaactin (α-SMA), with significant reduction in interleukin-1beta (IL1β) level in relation to diabetic group. Conclusion: In comparison to insulin administration alone, co-delivery of ANX with insulin throughout diabetes treatment was more effective in preserving the structure and function of the parotid glandHISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY ON THE POSSIBLE AMELIORATING EFFECTS OF ANTOX ON THE PAROTID GLAND OF RATS WITH STREPTOZOTOCIN-INDUCED DIABETES MELLITUS TYPE 1
Nadya ebasiry Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
BACKGROUND: Gentamicin is widely used broad spectrum aminoglycoside antibiotic. Despite its beneficial effects, gentamicin has considerable nephrotoxic effects. Salicylic acid is a phenolic compound that has anti-inflammatory, analgesic and antipyretic effect. It has also antioxidant activity that can counteract oxidative damages induced by adverse conditions in animals. OBJECTIVES: The work aims to detect the harmful changes in the rat kidney that occur after administration of gentamicin and to determine whether salicylic acid treatment attenuates gentamicin - induced nephrotoxicity. MATERIAL AND METHODS: Fifty healthy adult male Wister albino rats were obtained from the breading animal house, Faculty of Veterinary Medicine, Zagazig University. These animals were divided randomly and equally in to five groups. Each group contains ten rats. Group 1: Included control animals. Group 2: Included salicylic acid-treated animals. Group 3: Included gentamicin-treated animals. Group 4: Included animals treated with salicylic and gentamicin at the same time. Group 5: Included animals treated with gentamicin and remain for recovery. The rats were anesthetized with ether inhalation and sacrificed. The kidneys were removed and processed for light and electron microscopic examination. RESULTS: The histological study revealed that gentamicin causes severe nephrotoxicity. Exposure to gentamicin caused necrosis of tubular epithelial cells. The glomeruli were also affected. On the other hand, salicylic acid administration protected kidney tissue against the nephrotoxic effect caused by gentamicin treatment. Recovery from gentamicin treatment could occur spontaneously but it was slow and incomplete. CONCLUSION: Gentamicin administration leads to harmful changes in the structure of the rat kidney. Spontaneous recovery could occur but it is slow and incomplete. These nephrotoxic changes can be protected by co-therapy with salicylic acid
Nadya ebasiry Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Background: The cerebellum is the second largest part of the mammalian brain. It is a key regulator of coordinated sensory and musculoskeletal actions. The cerebellar cortex has a striking morphology consisting of folia and fissures and a variety of cells which are morphologically and functionally different, so it’s considered as an ideal model to study the development of the central nervous system in the mammals. The Objectives: The aim of this work was to study the prenatal and postnatal development of the albino rat cerebellar cortex considering its structure and maturation. Material And Methods: 35 healthy, non-pregnant female and 18 male albino rats weighing (200-250 g) were obtained from the animal house, Faculty of Medicine, Zagazig University. After mating and pregnancy, the rat embryos and offsprings were divided into 3 groups and 6 subgroups; Group A (11th, 16th&20th fetal rats), Group B (7th, 14th &21st postnatal days rats) and Group C (3 months old rats). The fetal rats (11th and 16th) were fixed as whole, while the remaining prenatal, postnatal and adult rats were dissected to obtain cerebella, which were processed for light and electron microscopic examinations, morphometric and immunohistochemical studies. Results: Albino rats at prenatal day 11 (E11) showed formation of the neural tube from the ectodermal layer. Albino rats at prenatal day 16 (E16) showed a demarcated cerebellar anlage (rhombic lip ( at the dorsal part of the metencephalon. The cerebellar cortex at prenatal day 20 (E 20) showed appearance of the general architecture. From outwards to inwards, it consisted of external granular, molecular, Purkinje cell, internal granular layers. Thickness of the external granular layer was maximum at postnatal day 7 (D7) then gradually decreased with age till disappearance in adult age. The molecular layer showed a gradual increase in thickness with age till reaching its maximum size at adult stage. Purkinje cells at (E20) and (D7) were not arranged in a definite layer. It appeared as a single layer between the molecular and internal granular layer at D14, D21 and adult. The internal granular was consisted of scattered small granule cells at E20 and D7. At D14 the internal granular layer became well differentiated and distinguished from the white matter. Immunohistochemistry showed a negative reaction for glial fibrillary acidic protein (GFAP) at E11 and E16. The first positive reaction for GFAP appeared at E20 then gradually increased till adult group. Conclusion: The study concluded that the cerebellar cortex undergoes differentiation and maturation during late prenatal and early postnatal ages early postnatal ages till the third week of life, corresponding to nearly the seventh postnatal month in human. Therefore the development of the cerebellum is very critical and sensitive during these periods makes it susceptible to malformationPRENATAL AND POSTNATAL DEVELOPMENTAL CHANGES OF THE CEREBELLAR CORTEX IN ALBINO RATS
Nadya ebasiry Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
International Immunopharmacology 2023; Volume 115: 109621 Background Ulcerative colitis (UC) is a global inflammatory bowel disease. Aime :This study aimed to assess the effects of icosapent ethyl on acetic acid-induced colitis in rats as well as the underlying mechanisms involved. Methods 36 male Wister rats were equally divided into Six groups: control, UC, mesalamine 100 mg/kg, icosapent 150mg/kg, icosapent 300 mg/kg, and EX527-icosapent 300 mg/kg groups. EXcept for control group, UC was induced by acetic acid instillation into colon. Drugs were administered once daily for one week then under thiopental anaesthesia, colons were excised. Colitis macroscopic and microscopic scores were assessed. A part of colon was homogenized for detection of malondialdehyde (MDA), inerleukin1 (IL-1β), tumor necrosis factor (TNF-α), superoxide dis-mutase (SOD), phosphorylated Akt (pAkt) and caspase 3 levels. Silent information regulator 1 (SIRT1), hemeoxygenase 1 (HO-1), and nuclear factor erythroid 2 (Nrf2) mRNA expressions were detected. Mallory-stained colonic sections were examined for collagen fibres detection. Immunohistochemistry of NF-κB and p53 expressions in colonic sections were assessed. Results There acetic acid induced colitis increments in MDA, IL-1β, TNF-α, and caspase 3 levels while decreased SOD, pAkt, SIRT1, HO-1, and Nrf2 with increased collagen fibres as well as NF- κB and p53. Icosapent decreased macro& microscopic colitis scores, MDA, IL-1β, TNF-α, and caspase 3 levels while increased SOD, pAkt, SIRT1, HO-1, and Nrf2 with decreased collagen fibres as well as NF-κB and p53. The effects of icosapent 300 mg/kg were similar to mesalamine. Icosapent effects were antagonized by EX527. Conclusion Icosapent alleviated acetic acid-induced colitis via its anti-inflammatory, Antioxidant, and anti-apoptotic effects mediated in part by SIRT1 pathway activationIcosapent ethyl alleviates acetic acid-induced ulcerative colitis via modulation of SIRT1 signaling pathway in rats
Imam Gomaa Imam Omar
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Groups
AbdulFattah Salah Mohamed Ibraahim
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The present investigation aims to evaluate the impacts of organic and inorganic fertilizers on the water parameters and physiological behaviors of an aquatic plant (Azolla sp.). The experiment used three groups: treatment with organic or inorganic fertilizer and a group with no fertilization as a control. Azolla sp. were grown in cement ponds that received different treatments. For water analysis, the obtained results clarified that fertilization resulted in no variation in the temperature or total hardness among different treatments. Organic fertilizer increased the dissolved phosphorus content, total hardness, and bicarbonate alkalinity, as well as the total phosphorus content, whereas inorganic treatment increased the pH, total ammonia content, and total nitrogen content. Regarding the biochemical composition of Azolla sp., the chlorophyll content showed no variation among different treatment groups, while organic matter showed high variation among different treatment groups. The highest values for ash and fat content were recorded in control ponds. The highest protein content was found in organic treatment ponds. The addition of fertilizers led to an increase in the tissue contents of N and P compared to the control. This increase was highest when Azolla sp. was fertilized with organic fertilizer. The atomic N:P ratio was low in tissues subjected to either treatment compared with the control. The doubling time of Azolla sp. was decreased by fertilization. It is concluded that different fertilizer systems have significant effect on physico-chemical and biological parameters of water. Fertilization positively affects Azolla sp. growth. Organic fertilizer was more efficient for the growth of Azolla sp., so it can be considered as a source of biofertilizer and green manure in areas where it spreads.
Fawzan Ismail Sedky
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
soft sets, soft groups
Hanim Khalid Mohamed Mohamed Saleem
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
A proposed educational map to achieve educational justice for some marginalized groups with special needs in Sharkia Governorate
Nahla Hassan Ahmed Gad
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
© 2019 Indian Journal of Otology | Published by Wolters Kluwer - Medknow90AbstractOriginal ArticleintroduCtionMultiple sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central nervous system (CNS). Disseminated neurological symptoms caused by acute and chronic inflammation include loss or alteration of sensation (numbness, paresthesia), of motor function (typically spastic paresis or complete paralysis), visual symptom such as blurring of vision, transient blindness, disorder of conjugate eye movements, bladder, bowel dysfunction, and cognitive impairment. MS patients require enduring medical and rehabilitative care. Fatigue is one of the most common symptoms reported by patients with MS, which is reported to affect between 50% and 80% of patients.[1]The diagnosis of MS is based on representing evidence of inflammatory-demyelinating harm within the CNS that is disseminated in both time and space. Diagnosis is through a combination of the clinical history, neurologic examination, magnetic resonance imaging, and the exclusion of other diagnostic possibilities. Other so-called “para-clinical” tests, including the examination of the cerebrospinal fluid, the usage of evoked potentials, urodynamic studies of bladder function, and ocular coherence tomography, may be helpful in forming the diagnosis of MS, but are often unnecessary.[2]MS is characterized by episodes (“attacks” or “relapses”) of neurologic dysfunction. The symptoms caused by these attacks vary significantly between patients and depend on the site of neurologic involvement. Commonly, patients may complain of numbness, tingling, weakness, vision loss, gait impairment, incoordination, imbalance, and bladder dysfunction. Between these attacks, in the relapsing-remitting (RR) phase of the illness, patients are neurologically stable.[3]Many patients who begin with RRMS progress to the secondary progressive phase of the illness, in which they have marked worsening of function and increasing of neurologic disability not related to any acute attacks that may or may not occur. About 66% of RRMS patients developed SPMS at an average time of 15 years,[4] while in a British Columbia cohort study, 58% of patients with relapsing MS advanced to SPMS after an average time of 19.1 years.[5]Objectives: To evaluate central auditory functions in multiple sclerosis (MS) patients. Subjects and Methods: Twenty Egyptian MS patients involved in the study and 20 healthy controls who were matched to MS group in age, gender, and literacy. They ranged in age from 30 to 50 years with a mean age 37.6 ± 5 in the study group versus 37.3 ± 4.2 in the control group. In this study, four screening tests were conducted for the assessment of central auditory processing: Gaps In Noise test (GIN), Arabic dichotic digits test (DDT), Pitch Pattern Sequence test (PPS), and last Arabic Speech In Noise test (SPIN). Results: The study showed elevated GIN test approximate threshold and depressed total score in MS patients compared to the control group, with no significant difference between both right and left ears. There was statistical significant depressed scores in study groups at PPS, speech intelligibility in noise, and DDTs. Conclusion: The findings of the current study add more evidence to the involvement of central auditory processing abilities in patients with MS. The assessment of central auditory function is highly recommended for all MS patients as a routine examination and can be used for monitoring the effectiveness of medication and related therapies for these patients
Nahla Hassan Ahmed Gad
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
AbstractPurposeBehavioral evaluation of language development is an important index for the usefulness of cochlear implantation. However, it could not apply to infants and very young children. It is useful to adopt an objective measure to examine speech discrimination in this population. Thus, the current study aimed to predict the different behavioral language performance (good versus poor) in cochlear implant (CI) recipients through the auditory cortical assessment of speech discrimination with mismatch negativity (MMN).MethodsThe study comprised 40 CI children who were divided into two groups according to their behavioral language evaluation outcomes: 20 good and 20 poor CI performers. They were age, gender, and socioeconomically matched. The MMN was examined and compared between both groups with finding out the relationship between MMN and different variables.ResultsMMN existed in all good performers and 87.5% of the poor performers. There were significantly shorter latency, larger amplitude, and a larger area of MMN in the good performers. The MMN results correlated with a significant predic-tive effect on the behavioral measures of language evaluation.ConclusionThe MMN is a clinically applicable objective measure of speech discrimination proficiency. Hence, it could be useful in CI programming and auditory cortical monitoring during rehabilitation.Keyword Cochlear implantation · Auditory cortical processing ·
Nahla Hassan Ahmed Gad
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Objectives: To evaluate central auditory functions in multiple sclerosis (MS) patients. Subjects and Methods: Twenty Egyptian MS patients involved in the study and 20 healthy controls who were matched to MS group in age, gender, and literacy. They ranged in age from 30 to 50 years with a mean age 37.6 ± 5 in the study group versus 37.3 ± 4.2 in the control group. In this study, four screening tests were conducted for the assessment of central auditory processing: Gaps In Noise test (GIN), Arabic dichotic digits test (DDT), Pitch Pattern Sequence test (PPS), and last Arabic Speech In Noise test (SPIN). Results: The study showed elevated GIN test approximate threshold and depressed total score in MS patients compared to the control group, with no significant difference between both right and left ears. There was statistical significant depressed scores in study groups at PPS, speech intelligibility in noise, and DDTs. Conclusion: The findings of the current study add more evidence to the involvement of central auditory processing abilities in patients with MS. The assessment of central auditory function is highly recommended for all MS patients as a routine examination and can be used for monitoring the effectiveness of medication and related therapies for these patients