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Advanced interpretable diagnosis of Alzheimer's disease using SECNN-RF framework with explainable AI
Faculty
Computer Science
Year:
2024
Type of Publication:
ZU Hosted
Pages:
1456069
Authors:
Wael Said AbdelMageed Mohamed
Staff Zu Site
Abstract In Staff Site
Journal:
Frontiers in Artificial Intelligence .Frontiers Media S.A
Volume:
7
Keywords :
Advanced interpretable diagnosis , Alzheimer's disease using
Abstract:
Early detection of Alzheimer's disease (AD) is vital for effective treatment, as interventions are most successful in the disease's early stages. Combining Magnetic Resonance Imaging (MRI) with artificial intelligence (AI) offers significant potential for enhancing AD diagnosis. However, traditional AI models often lack transparency in their decision-making processes. Explainable Artificial Intelligence (XAI) is an evolving field that aims to make AI decisions understandable to humans, providing transparency and insight into AI systems. This research introduces the Squeeze-and-Excitation Convolutional Neural Network with Random Forest (SECNN-RF) framework for early AD detection using MRI scans. The SECNN-RF integrates Squeeze-and-Excitation (SE) blocks into a Convolutional Neural Network (CNN) to focus on crucial features and uses Dropout layers to prevent overfitting. It then employs a Random Forest classifier to accurately categorize the extracted features. The SECNN-RF demonstrates high accuracy (99.89%) and offers an explainable analysis, enhancing the model's interpretability. Further exploration of the SECNN framework involved substituting the Random Forest classifier with other machine learning algorithms like Decision Tree, XGBoost, Support Vector Machine, and Gradient Boosting. While all these classifiers improved model performance, Random Forest achieved the highest accuracy, followed closely by XGBoost, Gradient Boosting, Support Vector Machine, and Decision Tree which achieved lower accuracy.
Author Related Publications
Wael Said AbdelMageed Mohamed, "A big data approach to sentiment analysis using greedy feature selection with cat swarm optimization-based long short-term memory neural networks", Springer Nature, 2018
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Wael Said AbdelMageed Mohamed, "High-Precision Brain Tumor Diagnosis Using SECNN-MNet Framework and Explainable AI", Springer Nature Link, 2025
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Wael Said AbdelMageed Mohamed, "Deception and cloud integration: A multi-layered approach for DDoS detection, mitigation, and attack surface minimization in SD-IoT networks", .Elsevier Ltd, 2025
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Wael Said AbdelMageed Mohamed, "Reinforcement Learning for Industrial Automation: A Comprehensive Review of Adaptive Control and Decision-Making in Smart Factories", MDPI, 2025
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Wael Said AbdelMageed Mohamed, "RAUM-GANs: A Multi-Layer GAN-Enhanced Framework for Accurate Multiple Sclerosis Lesion Segmentation in MRI", Nature Portfolio, 2025
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Department Related Publications
Ibrahiem Mahmoud Mohamed Elhenawy, "BERT-CNN: A Deep Learning Model for Detecting Emotions from Text", Tech Science Press, 2021
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Ahmed Raafat Abass Mohamed Saliem, "BERT-CNN: A Deep Learning Model for Detecting Emotions from Text", Tech Science Press, 2021
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Ahmed Raafat Abass Mohamed Saliem, "Using General Regression with Local Tuning for Learning Mixture Models from Incomplete Data Sets", ScienceDirect, 2010
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Ahmed Raafat Abass Mohamed Saliem, "On determining efficient finite mixture models with compact and essential components for clustering data", ScienceDirect, 2013
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Ahmed Raafat Abass Mohamed Saliem, "Unsupervised learning of mixture models based on swarm intelligence and neural networks with optimal completion using incomplete data", ScienceDirect, 2012
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