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Cupressus arizonica Greene: Phytochemical Profile and Cosmeceutical and Dermatological Properties of Its Leaf Extracts
Faculty
Pharmacy
Year:
2023
Type of Publication:
ZU Hosted
Pages:
Authors:
Mona Fouad Mahmoud Abdelaziz
Staff Zu Site
Abstract In Staff Site
Journal:
Molecules MDPI
Volume:
Keywords :
Cupressus arizonica Greene: Phytochemical Profile , Cosmeceutical
Abstract:
For many decades, natural resources have traditionally been employed in skin care. Here, we explored the phytochemical profile of the aqueous and ethanolic leaf extracts of Cupressus arizonica Greene and assessed their antioxidant, antiaging and antibacterial activities in vitro. Liquid chromatography–mass spectrometry (LC-MS/MS) analysis led to the tentative identification of 67 compounds consisting mainly of phenolic and fatty acids, diterpene acids, proanthocyanidins and flavonoid and biflavonoid glycosides. The aqueous extract demonstrated substantial in vitro antioxidant potential at FRAP and DPPH assays and inhibited the four target enzymes (collagenase, elastase, tyrosinase, and hyaluronidase) engaged in skin remodeling and aging with IC50 values close to those of the standard drugs. Moreover, the aqueous extract at 25 mg/mL suppressed biofilm formation by Pseudomonas aeruginosa, a bacterial pathogen causing common skin manifestations, and decreased its swarming and swimming motilities. In conclusion, C. arizonica leaves can be considered a promising candidate for potential application in skin aging.
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Department Related Publications
Ehsan Mahmoud Abdelaziz Abozied, "12) Chemical Constituents of Gomphocarpus Sinaicus Boiss, Family Asclepiadceae.Growing in Egypt", لايوجد, 1900
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Ehsan Mahmoud Abdelaziz Abozied, "13) Macro- and Micromorphology of the Flower and Fruit of Gomphocarpus Sinaicus Boiss. Family Asclepiadaceae. Growing in Egypt", لايوجد, 1900
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Ehsan Mahmoud Abdelaziz Abozied, "29) Improved Heigh-preformance liquid chromatographic Determination of Glycyrrhizin in Licorice and pharmaceutical preparations", لايوجد, 1900
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Samih Ibrahim Ahmed Eldhmy , "pharmacognostical Study of Some Plants Belonging to Compositae", لايوجد, 1900
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Afaf Alsayed Ali Abdelghanie, "A New Quantitative Method for Estimation of Haemolytic Saponins in Plants", لايوجد, 1900
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