ABSTRACT Background: Servant leadership is a form of moral-based leadership where leaders tend to prioritize the fulfillment of the needs of followers, rather than satisfying their personal needs. Although the concept is not new among academics and nursing, it has received growing consideration due to the fact that it can positively affect a series of individual and organizational creativity and self-efficacy. Aim: Investigate the relationship between servant leadership, self-efficacy, and the creativity of staff nurses. Subjects and Method: A descriptive correlational study design was used to conduct this study. Setting: The study was conducted at Zagazig University Hospitals. Subjects: A stratified random sample was selected from nurses (n= 375). Tools: Servant leadership assessment instrument, Employee Creativity scale, and Self-Efficacy Scale. Results: 61.9% of studied nurses report that their leader had a high level of servant leadership. Also, 54.1% of studied nurses had a moderate level of self-efficacy. In addition, 51.5% of studied nurses had a high level of creativity. Conclusion: There is a highly statistically significant correlation between servant leadership and both self-efficacy and creative activity. There was also a statistically significant correlation between creative activity and self-efficacy. Recommendations: Health care organizations should adopt a servant-leadership philosophy and establish servant leadership requirements for nurse managers to develop nurse leaders with a key “servant” orientation and mindset (e.g., emphasizing concerns for followers and prioritizing creativity and self-efficacy among nurses)." ----------------------------------------------------------------------------------------- Keywords: Servant Leadership, Creativity, Self – Efficacy and Staff Nurses.