Intranasal thermosensitive hydrogel of agomelatine solid dispersion for better management of depression

Faculty Pharmacy Year: 2023
Type of Publication: ZU Hosted Pages:
Authors:
Gehan Fathy Attia Elsayed Balata
Journal: Journal of Drug Delivery Science and Technology Elsevier B.V Volume: Volume 88
Keywords : Intranasal thermosensitive hydrogel , agomelatine solid dispersion    
Abstract:
Agomelatine (AGM) is a unique melatonergic antidepressant drug. However, it possesses low aqueous solubility, first-pass metabolism, and reduced bioavailability. The aim of the current study was to formulate AGM in an intranasal gel to achi
    
     
 
       

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  • Gehan Fathy Attia Elsayed Balata, "Controlled Crystallization as a Tool to Enhance the Dissolution and Anti-Inflammatory Properties of Indomethacin", Journal of Pharmacy Research, 2012 More
  • Gehan Fathy Attia Elsayed Balata, "Improvement of solubility and dissolution properties of ketoconazole by solid dispersions and inclusion complexes", Ketoconazole solid dispersions and inclusion complexes/Asian Journal of Pharmaceutical Sciences, 2010 More
  • Gehan Fathy Attia Elsayed Balata, "Propolis organogel as a novel topical delivery system for treating wounds", Drug Deliv, 2014; 21(1): 55–61, 2014 More
  • Gehan Fathy Attia Elsayed Balata, "Preparation and characterization of domperidone solid dispersions", Pak. J. Pharm. Sci., 2012 More
  • Gehan Fathy Attia Elsayed Balata, "Improvement of Solubility and Dissolution Properties of Clotrimazole by Solid Dispersions and Inclusion Complexes", Indian Journal of Pharmaceutical Sciences, 2011 More

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