Intranasal thermosensitive hydrogel of agomelatine solid dispersion for
better management of depression

Faculty	Pharmacy	Year:	2023
Type of Publication:	ZU Hosted	Pages:
Authors:	Staff Zu Site Abstract In Staff Site
Journal:	Journal of Drug Delivery Science and Technology Elsevier B.V	Volume:	Volume 88

Keywords :	Intranasal thermosensitive hydrogel , agomelatine solid dispersion
Abstract:	Agomelatine (AGM) is a unique melatonergic antidepressant drug. However, it possesses low aqueous solubility, first-pass metabolism, and reduced bioavailability. The aim of the current study was to formulate AGM in an intranasal gel to achi

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