Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages: 593–598
Authors:
Journal: Gene Therapy nature Volume:
Keywords : Activation , TLR9 , incorporated pDNA within PEG-coated lipoplex    
Abstract:
Cationic liposome represents a promising alternative to viral vectors for the delivery of therapeutic genes. For in vivo use, surface modification of the liposome with polyethylene glycol (PEG) is frequently applied to achieve gene-express
   
     
 
       

Author Related Publications

  • Amr Selim Ahmed Ali Abu Lila, "Treatment of pulmonary arterial hypertension by vardenafil-solid dispersion lozenges as a potential alternative drug delivery system", Elsevier, 2020 More
  • Amr Selim Ahmed Ali Abu Lila, "Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Efficacy of SPG-ODN 1826 Nanovehicles in Inducing M1 Phenotype through TLR-9 Activation in Murine Alveolar J774A.1 Cells: Plausible Nano-Immunotherapy for Lung Carcinoma", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Folic acid-conjugated raloxifene-loaded graphene-based nanocarrier: Fabrication, characterization and antitumor screening", ELSEVIER, 2021 More

Department Related Publications

  • Mahmoud Mokhtar AhmedIbrahiem, "Phase Study and Characterization of Certain Developed Multicomponent Colloidal Systems and their Potential Application As Carriers for An Antimicrobial Agent", لايوجد, 1900 More
  • Amr Selim Ahmed Ali Abu Lila, "Ex-vivo/in-vitro anti-polyethylene glycol (PEG) immunoglobulin M production from murine splenic B cells stimulated by PEGylated liposome", J.Stage, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model: synergy or antagonism?", Elsevier, 2012 More
  • Azza Ali Hassan Solyman, "Formulation and evaluation of metformin hydrochloride-loaded niosomes as controlled release drug delivery system", Informa health, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model", Elsevier, 2009 More
Tweet