Secukinumab and Black Garlic Downregulate OPG/RANK/RANKL Axis and Devitalize Myocardial Interstitial Fibrosis Induced by Sunitinib in Experimental Rats

Faculty Pharmacy Year: 2023
Type of Publication: ZU Hosted Pages:
Authors:
Yasmin Kasem Mahmoud
Journal: Life MDPI Volume:
Keywords : Secukinumab , Black Garlic Downregulate OPG/RANK/RANKL Axis , Devitalize    
Abstract:
Sunitinib has been associated with several cardiotoxic effects such as cardiac fibrosis. The present study was designed to explore the role of interleukin (IL)-17 in sunitinib-induced myocardial fibrosis (MF) in rats and whether its neutral
    
     
 
       

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  • Yasmin Kasem Mahmoud, "Empaglifozin ameliorates liver fbrosis in NASH rat model via targeting hepatic NF‑κB/SOX9/OPN signaling and osteocalcin level", Springer nature, 2023 More
  • Yasmin Kasem Mahmoud, "Policosanol ameliorates renal inflammation and pyroptosis in hypercholesterolemic rabbits via modulation of HMGB1/PI3K/mTOR/NLRP3/Caspase-1 pathway", Elsevier Ltd., 2022 More
  • Yasmin Kasem Mahmoud, "10-Dehydrogingerdione Attenuates Tramadol-Induced Nephrotoxicity by Modulating Renal Oxidative Stress, Inflammation and Apoptosis in Experimental Rats: Role of HO-1 Activation and TLR4/NF-κB/ERK Inhibition", MDPI, 2022 More
  • Yasmin Kasem Mahmoud, "Infliximab ameliorates tumor necrosis factor-alpha exacerbated renal insulin resistance induced in rats by regulating insulin signaling pathway", Elsevier B.V, 2020 More

Department Related Publications

  • Ahmed Shafea Mahmoud Morsy, "قيمه سمك الطانه والطبقة الوسطي للشريان السباتي والفخذي كعامل غير نافذ للتنبؤ بمرض الشريان التاجي", مجلة القلب المصرية, 2001 More
  • Ahmed Shafea Mahmoud Morsy, "تاثير توسيع الصمام الميترالي بالقسطره البالونية علي الارتجاع الوظيفي للصمام ثلاثي الشرفات وارتفاع ضغط الشريان الرئوي", مجلة جامعة الزقازيق الطبية, 2000 More
  • Tarek Abdelmoniem Abdelaziz, "Human C-reactive protein gene polymorphism andmetabolic syndrome are associated with premature coronary artery disease", Elsevier, 2013 More
  • Tarek Abdelmoniem Abdelaziz, "Synergistic Effect Between Lipoprotein Lipase and Apolipoprotein C3 Genes in Determining the Severity of Coronary Artery Disease", Springer, 2013 More
  • Eslam Alsayed Mohamed Mohamed Shehata, "Mitral annulus time intervals for assessment of left ventricular systolic function in ischemic cardiomyopathy", European Journal of Heart Failure Supplements (2012) 11, S128–S177, 2012 More
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