ABSTRACT Introduction: Entrepreneurship is a mindset that shows a person's motivation and ability to detect a business opportunity and pursue it, in order to create new value or achieve success. Aim: the aim of this study is to assess the influence of entrepreneurial leadership, perceived role of university support and teacherpreneurship on students' entrepreneurial intentions and opportunity recognition. Study design: Descriptive correlational study design was used. Sample: A convenience sample of all available faculty educators (115 faculty educators). In addition, a stratified random sample of nursing students from each academic year (345 nursing students). Tools of data collection: Faculty Educator’s questionnaire sheet, which includes four parts: 1) Personal characteristics of the faculty educators, 2) Entrepreneurial leadership 3) Perceived university support and 4) Teacherpreneurship. Nursing student’s questionnaire sheet, which includes three parts: 1) Personal characteristics of nursing student 2) Entrepreneurial intentions and 3) Opportunity recognition. Results: The results revealed that the entrepreneurial leadership was significantly and positively correlated to perceived role of university support, teacherpreneurship, students' entrepreneurial intention, and students' opportunity recognition. Conclusion: entrepreneurial leadership and university support have positive and significant influence on teacherpreneurship. As well, Teacherpreneurship mediates the influence of entrepreneurial leadership and university support on students' entrepreneurial intentions and students' opportunity recognition. Recommendations: Higher education institutes play a critical role in furthering the self-efficacy of entrepreneurial actions and positive attitude toward entrepreneurship among students by designing an instructional program that facilitates their entrepreneurship by allowing them to change their mindset, attitudes, and intentions about entrepreneurship.