Abstract Vocational students considered young workers who are usually injured at the worksite. Education and awareness are necessitated for them. Background: Clinical teaching is a very important mission of nursing education because the clinical experiences connect theory to practice. Where students who achieve good practice and safety technology in the available health facility and teaching atmosphere would establish nursing competencies through practicing partnerships [1]. Nursing education is the most viable study to continue the education process for practice [2]. Aim: This study aims to develop strategies to overcome the challenges facing nursing's clinical teaching. Method: Current investigation was conducted at Nursing faculty, Zagazig University on 3 studied groups: first; clinical instructors (77), second; faculty students (330) and third, jury (7). Tools: Three tools were utilized for data collection, including challenges assessment questionnaire and two experts' opinionnaires format. Results: The most frequent challenges facing nursing’s clinical teaching are: the clinical instructor was not concerned with the issues that students raised (92.2), the variance between faculty goals for students and clinical site goals (87), students didn't have the required clinical skills in the clinical setting (85.2), and, the clinical instructors enforce students for involvement in practice (82.1). Conclusion: The questionnaire of assessing nursing clinical teaching challenges is reliable, valid and usable. The strategies for overcoming nursing clinical teaching challenges was developed and validated. Keywords: clinical teaching, challenges, students, instructors, nursing education, development, strategies