Background: Children with severe or profound hearing loss benefit significantly from cochlear implantation, which helps to build listening skills, communication abilities, social skills, and involvement, as well as allowing children to grow in their life as a method of earning a living. Objective: This study aimed to evaluate the effect of empowerment program on parents' self competence regarding care of their children with cochlear implantation. Methods: The research was carried out at Bahteem Specialized Hospital's Phoniatric Unit of the Ear, Nose, and Throat department. A total of (75) parents accompanied their children to the cochlear implantation procedure. A structured interviewing questionnaire sheet, a child medical data sheet, a checklist of parents' reported practices, and a Parenting Sense of Competency Scale were employed. Results: there was a highly statistically significant difference in parents' knowledge, reported practice and self competence level regarding care for their children with cochlear implantation pre and post empowerment program implementation. while, there was no statistically significant difference in parents' knowledge, reported practice and self competence level regarding care for their children with cochlear implantation between post and after three months of empowerment program implementation. Furthermore, parents had a high self competence post program and follow up after three months compared with pre program implementation. Conclusion: After the empowerment program was implemented, parents' knowledge, reported practice, and self-competence in caring for their children with cochlear implantation improved. Recommendation: Provide a continuous educational program for parents involved in their children's cochlear implantation care.