Fluoroquinolone-3-carboxamide Amino Acid Conjugates: Synthesis, Antibacterial Properties And Molecular Modeling Studies

Faculty Pharmacy Year: 2021
Type of Publication: ZU Hosted Pages: 71-84
Authors:
Tarek Mohamed Salah Rashad
Journal: Medicinal Chemistry Bentham Science Publishers Volume: 17
Keywords : Fluoroquinolone-3-carboxamide Amino Acid Conjugates: Synthesis, Antibacterial    
Abstract:
Abstract: Background: Bacterial infections are considered as one of the major global health threats, so it is very essential to design and develop new antibacterial agents to overcome the drawbacks of existing antibacterial agents. Method: The aim of this work is to synthesize a series of new fluoroquinolone-3-carboxamide amino acid conjugates by molecular hybridization. We utilized benzotriazole chemistry to synthesize the desired hybrid conjugates.
    
     
 
       

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