Journal: |
Egyptian Journal of Obesity, Diabetes and Endocrinology
Wolters Kluwer - Medknow
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Abstract: |
Background
The relationship among vitamin D (VD) deficiency, metabolic syndrome, and type 2
diabetes mellitus (T2DM) is still doubtful, whether it is causal or jumbling.
Aim
To assess the link between VD deficiency and T2DM in old obese Egyptian patients
and to evaluate the correlation between VD and some variables in T2DM.
Patients and methods
The study was conducted in Internal Medicine and Clinical Pathology Departments,
Zagazig University Hospitals, from 02/2018 to 10/2018, involving 60 patients, aged
more than or equal to 60 years, comprising 18 males and 42 females, who were
divided into two groups: 30 patients with T2DM and 30 patients were proved to be
without diabetes during the sample collection. Each group was subdivided
according to their BMI into obese and nonobese.
Results
A highly significant difference was detected in VD level between nondiabetes and
diabetes groups (23.85±12.1 vs. 16.2±7.9 ng/ml, respectively, P=0.001). VD
deficiency was significantly higher in diabetes group (χ2=10.38, P=0.006).
Insignificant difference was detected regarding age (67.3±2.4 vs. 67.7±2.5,
P=0.5) and BMI (30.7±5.1 vs. 32.7±5.3 kg/m2, P=0.14) between nondiabetes
and diabetes. There was a highly significant difference in VD level between
obese nondiabetes and obese diabetes (27±17.5 vs. 13.3±8.2 ng/ml,
respectively, P=0.001). A positive correlation was detected between VD level
and fasting blood sugar (r=0.438, P=0.032), whereas a negative correlation
between VD level and BMI in diabetes group only (r=−0.437, P=0.033) and in
obese group only (r=−0.515, P=0.012).
Conclusion
Approximately 78.3% of patients had hypovitaminosis D (51.7% deficiency and
26.6% insufficiency). VD deficiency was significantly higher in diabetes group and in
obese diabetics.
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