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Ankle Brachial Index As A Monitor Of Diabetes type 2 Microvascular Complications
Faculty
Medicine
Year:
2019
Type of Publication:
ZU Hosted
Pages:
Authors:
Amira Ahmed Mahmoud Monier
Staff Zu Site
Abstract In Staff Site
Journal:
Med. J. Cairo Univ Med. J. Cairo Univ
Volume:
Keywords :
Ankle Brachial Index , , Monitor , Diabetes type
Abstract:
Abstract Background: Peripheral artery disease (PAD) has been linked with diabetic microvascular complications. However, many patients do not show typical symptoms. Ankle– brachial index (ABI) is reported to be a simple and useful method to estimate cardiovascular risks. Aim: to determine whether Anklebrachial index could be a useful monitor of development of micro vascular complications in type 2 diabetes. Patients and Methods : A cross sectional study included 93 patients, classified into two groups: Group I (Control group) consistsed of 10 healthy individuals. Group II (Patient Group): consisted of 83 diabetes Type2 patients diagnosed according to ADA criteria; who were further subdivided according to presence or absence of microvascular complications into two groups: Group IIa: 10 Diabetics without microangiopathy and Group IIb: 73 Diabetics with microangiopathy. All the study members were subjected to clinical Evaluation, fundus examination, serial measurement of blood pressure, Fasting & postprandial blood glucose, HbA1c, serum Creatinine, Urinary Albumin and ABI. Results: Our results showed significant higher BMI and lower ABI in diabetic groups compared to control (p < 0.05 ); where fasting blood glucose, postbrandial blood glucose, HbA1c and serum creatinine were significantly elevated diabetic groups compared to control (p < 0.05 ). A significant negative correlations (p< 0.000) between BMI, HbA1c and duration of DM with ABI. The Incidance of microvacular complications (retinopathy, nephropathy & neuropathy) was significantly higher (p 0.00) in complicated diabetic group (group IIb) compared to control and IIa groups. The average ABI was significantly lower (p < 0.05 ) among complicateddiabetic group (group IIb) regarding retinopathy (proliferative & non proliferative), nephropathy (micro & macroalbuminria) and neuropathy (mild, moderate & sever) . Conclusion: Low ABI is common in patients with T2D. The ABI is a simple, reproducible, and cost-effective screening test for diagnosing microvascular complications in diabetes type 2 patients. ABI screening should be performed in diabetic population for early evaluate of microvascular complications.
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