Gastric ulcer is one of the serious problems and diseases for many of patients that cause a lot of sufferings to these patients and its cause may be either due to stress or by using of a lot of anti-inflammatory drugs or even due to higher acidity of the stomach. So the present study was extended to investigate the anti-ulcer capacities of ranitidine drug alone and in combination with fenugreek, ginger and peppermint oils on both stress and indomethacin induced gastric mucosal ulcer. Gastric mucosa was evaluated, some serum antioxidant parameters were measured and GCMs analysis was performed for the three oils. One hundred and ten male albino rats were group into 2 main groups one normal control group and five groups in which stress gastric ulcers were induced experimentally and five indomethacin induced gastric ulcer groups. The data indicated that both stress and indomethacin induced gastric ulcer induced oxidative stress. The results revealed that both ginger and fenugreek oils have an antiulcer and gastro protective properties. Surprisingly, the stress induced ulcer model showed that ginger and fenugreek oils were superior to ranitidine in treatment of gastric ulcer. Ginger and fenugreek oils showed a promising antioxidant effect represented by increased catalase (CAT) and Super oxide dismutase (SOD) activities and decreased malondialdehyde (MDA) values. Peppermint oil on the other hand has lower properties of being an antiulcerogenicor a gastroprotective agent despite its importance as herbal medicine with so many benefits.