Development of Sedative Dexmedetomidine Sublingual In Situ Gels: In Vitro and In Vivo Evaluations

Faculty Pharmacy Year: 2022
Type of Publication: ZU Hosted Pages: 220
Authors:
Nora Gamal Mohamed Abdallah Essa
Journal: Pharmaceutics MDPI Volume: 14
Keywords : Development , Sedative Dexmedetomidine Sublingual , Situ Gels:    
Abstract:
Intravenous dexmedetomidine (DEX) is currently approved by the FDA for the sedation of intubated patients in intensive care units to reduce anxiety and to augment postoperative analgesia. Bradycardia and hypotension are limitations associat
    
     
 
       

Author Related Publications

  • Nora Gamal Mohamed Abdallah Essa, "Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides", Elsevier Inc, 2014 More
  • Nora Gamal Mohamed Abdallah Essa, "Buccoadhesive tablets for delivery of verapamil Hcl: Design, in-vitro analysis and in-vivo evaluation", Bull. Pharm. Sci., Assiut University, 2012 More
  • Nora Gamal Mohamed Abdallah Essa, "New approach for administration of doxazosin mesylate: comparative study between liquid and solid self-nanoemulsifying drug delivery systems", JK Welfare & Pharmascope Foundation, 2021 More
  • Nora Gamal Mohamed Abdallah Essa, "Topical silymarin versus hydroquinone in the treatment of melasma: A comparative study", Wiley, 2019 More
  • Nora Gamal Mohamed Abdallah Essa, "Engineering of smart nanoconstructs for delivery of glucagon-like peptide-1 analogs", Elsevier B.V., 2021 More

Department Related Publications

  • Amr Selim Ahmed Ali Abu Lila, "Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production", nature, 2014 More
  • Nagia] Ahmed Alameen Elmgrab, "Oestradiol permeation through human skin and silastic membrane: effects of propylene glycol and supersaturation", Elsevier B.V., 1995 More
  • Abdullah Mohammed Abdullah Ayub, "Sulpiride microemulsions as antipsychotic nasal drug delivery systems: In-vitro and pharmacodynamic study", Journal of Drug Delivery Science and Technology, 2016 More
  • Hanan Mohamed Mahmoud Mostafa Elnahas, "Optimization and Characterization of Eudragit S 100 Microsponges of Fluconazole", www.ijtrd.com, 2016 More
  • Azza Ali Hassan Solyman, "Optimization and Characterization of Eudragit S 100 Microsponges of Fluconazole", www.ijtrd.com, 2016 More
Tweet