Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Immune response and susceptibility of Nile tilapia fish to Aeromonas hydrophila infection following the exposure to Bifenthrin and/or supplementation with Petroselinum crispum essential oil
Faculty
Veterinary Medicine
Year:
2021
Type of Publication:
ZU Hosted
Pages:
Authors:
Samah Ramadan Elsayed Khallil
Staff Zu Site
Abstract In Staff Site
Journal:
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY Elseiver
Volume:
Keywords :
Immune response , susceptibility , Nile tilapia fish
Abstract:
Bifenthrin (BF) is a widely used 3rd generation type I pyrethroid with a potential toxic effect in fish. Nevertheless, its effect on the immune system remains unclear. In the present study, Oreochromis niloticus was exposed to BF at 0.68 mu g/L for 60 days, followed by evaluating the hematological, biochemical, and immunological responses. Additionally, the potential of parsley (Petroselinum crispum) essential oil (PEO) to ameliorate the BFinduced toxic insults was explored. Our data have shown reductions in the growth performance with alterations observed in the hematological variables, protein profile and serum biomarkers of stress. DNA oxidative damage was evidenced by elevation of serum 8-hydroxy-2-deoxyguanosine (8-OHdG) content. BF-exposed fish presented also decline in serum lysozyme activity and levels of immunoglobulins (IgG and IgM) and nitric oxide (NO), with diminished resistance to Aeromonas hydrophila challenge. Furthermore, the RT-PCR analysis showed an upregulated expression pattern of immune - related genes including interleukin 1 beta (IL-1 beta), interferon - alpha (IFN alpha) and tumor necrosis factor - alpha (TNF-alpha) genes in the liver tissue. Dietary co-supplementation of PEO at 1 or 2 mL/kg diet with concomitant BF exposure, alleviated the adverse effects of the insecticide in a dose-dependent manner. The observations from this study demonstrate the immunomodulation by BF and provide further insight into the protective properties of PEO and strengthen its applicability as a promising feed supplement to fish.
Author Related Publications
Samah Ramadan Elsayed Khallil, "Spirulina platensis attenuates the associated neurobehavioral and inflammatory response impairments in rats exposed to lead acetate", elseiver, 2018
More
Samah Ramadan Elsayed Khallil, "Differential susceptibility of kidneys and livers to proliferative processes and transcriptional level of the genes encoding desmin, vimentin, connexin 43, and nestin in rats exposed to furan", elseiver, 2018
More
Samah Ramadan Elsayed Khallil, "Effect of dietary supplementation with Spirulina platensis on Atrazine-induced oxidative stress-mediated hepatic damage and inflammation in the common carp (Cyprinus carpio L.)", elseiver, 2018
More
Samah Ramadan Elsayed Khallil, "Intermediate filament protein expression pattern and inflammatory response changes in kidneys of rats receiving doxorubicin chemotherapy and quercetin", elseiver, 2018
More
Samah Ramadan Elsayed Khallil, "The Cytotoxic and Ultrastrctural Perturbations of Aluminum Exposed Nile Catfish with Special Reference to the Mitigating Effect of Vitamin C", life science journal, 2012
More
Department Related Publications
Tamer Ahmed Abdelfatah Ismaiel, "Green tea ameliorates adriamycin toxicity in rats.", لايوجد, 1900
More
Hussein Ahmed Heshmat , "تأثير برنامجين لأهتزاز الجسم الكلى و المقاومة على كثافة العظام ", لايوجد, 1900
More
Adel Abdeltawab Khalil Elbadry, "The effect of sex steroids on the brain constituents of the rat. IV-testosterone: ", لايوجد, 1900
More
Adel Abdeltawab Khalil Elbadry, "Diabetogenic effect of ?-sitosterol. Int. Conf. On Chem. & Biotech. of Biologically active products.", لايوجد, 1900
More
Adel Abdeltawab Khalil Elbadry, "Hazards from exposure to 50 Hz, 1Gauss magnetic field on reproduction in male albino rats.", لايوجد, 1900
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف