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Efficacy of grape seed hydro-alcoholic extract in the treatment of experimentally Pasteurella multocida infected rabbits
Faculty
Veterinary Medicine
Year:
2021
Type of Publication:
ZU Hosted
Pages:
Authors:
Azza Ahmed Abdelghafar Gala
Staff Zu Site
Abstract In Staff Site
Journal:
veterinary medicine and science Wiley
Volume:
Keywords :
Efficacy , grape seed hydro-alcoholic extract , , treatment
Abstract:
Pasteurellosis is one of the rabbit's most bacterial severe diseases and leads to considerable financial damages in large production systems worldwide. Antibiotic use in animals may lead to antibiotic residues in animal products, including meat. Therefore, this study was designed to evaluate the potential role of grape seed extract (GSE) in treating Pasteurella multocida infection in rabbits. For this purpose, 45 weaned male New Zealand rabbits were divided into three groups; control, infected and infected-GSE treated. Experimental P. multocida infection in rabbits induced a remarkable decrease in body weight, body weight gain, as well as microcytic hypochromic anaemia, leucocytosis, neutrophilia and lymphocytopenia. Also, a significant increase in the hepatic and renal injury biomarkers, in interleukin-6, total globulin, α, β and γ globulins, as well as a marked reduction in total protein and albumin, were recorded in the P. multocida-infected rabbits. Treatment of infected rabbits with GSE modulated most of these altered parameters. This study endorses the administration of GSE for the treatment of Pasteurellosis in rabbits. Further studies are required to identify the possible additional effects, appropriate doses and duration of the GSE therapy in rabbits Pasteurellosis.
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Azza Ahmed Abdelghafar Gala, "The Relationship between Gastroprotective Effect of Propolis and Its Antioxidant activity", كلية الطب البيطرى, 2010
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Azza Ahmed Abdelghafar Gala, "Clinicopathological Studies On Hepato-Nephro-Protective Effect Of Salvadora Persica Extract In Albino Rats", كلية الطب البيطرى, 2013
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Azza Ahmed Abdelghafar Gala, "Protective effect of Zingiber officinale (ginger) on doxorubicin induced oxidative cardiotoxicity in rats.", Life Science Journal, 2013
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Azza Ahmed Abdelghafar Gala, "COMARSION OF PUNICA PEEL AND OXYTETRACYCLIN ON AEROMONAS HYDROPHILA CHALLENGED CLARIAS GARIEPINUS", The Global Journal of Fisheries and Aqua. Res. - Vol. No. 5, (2012) - ISSN 18191, 2012
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Azza Ahmed Abdelghafar Gala, "Toxic effects of sub-chronic exposure of male albino rats to emamectin benzoate and possible ameliorative role of Foeniculum vulgare essential oil", Elsevier, 2015
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Department Related Publications
Ahmed Abdoh Said Muhmmd, "Pharmacological Effects of Fish and Soyabean oils in Sheep", لايوجد, 1900
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Ahmed Abdoh Said Muhmmd, "العلاقة بين تاثيرصمغ النحل كواقى للمعدة وقدرتة كمضاد للاكسدة ", لايوجد, 1900
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Alsayed Ahmed Abdelazeez , "Efficacy and pharmacokinetic pattern of norfloxacin in both healthy and diseased chickens. proceeding from the 1st Conf. on The role of Scientific Research and Technological Development in the Protection of Environment Against Pollution ", لايوجد, 1900
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Alsayed Ahmed Abdelazeez , "A prelude to the clinical use of fertagyl and prosolvin in male infertility ", لايوجد, 1900
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Hosnah Abdelfadiel, " Biochemical, residual and histopathological studies in catfish (C. ", لايوجد, 1900
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