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Efficacy of grape seed hydro-alcoholic extract in the treatment of experimentally Pasteurella multocida infected rabbits
Faculty
Veterinary Medicine
Year:
2021
Type of Publication:
ZU Hosted
Pages:
Authors:
Azza Ahmed Abdelghafar Gala
Staff Zu Site
Abstract In Staff Site
Journal:
veterinary medicine and science Wiley
Volume:
Keywords :
Efficacy , grape seed hydro-alcoholic extract , , treatment
Abstract:
Pasteurellosis is one of the rabbit's most bacterial severe diseases and leads to considerable financial damages in large production systems worldwide. Antibiotic use in animals may lead to antibiotic residues in animal products, including meat. Therefore, this study was designed to evaluate the potential role of grape seed extract (GSE) in treating Pasteurella multocida infection in rabbits. For this purpose, 45 weaned male New Zealand rabbits were divided into three groups; control, infected and infected-GSE treated. Experimental P. multocida infection in rabbits induced a remarkable decrease in body weight, body weight gain, as well as microcytic hypochromic anaemia, leucocytosis, neutrophilia and lymphocytopenia. Also, a significant increase in the hepatic and renal injury biomarkers, in interleukin-6, total globulin, α, β and γ globulins, as well as a marked reduction in total protein and albumin, were recorded in the P. multocida-infected rabbits. Treatment of infected rabbits with GSE modulated most of these altered parameters. This study endorses the administration of GSE for the treatment of Pasteurellosis in rabbits. Further studies are required to identify the possible additional effects, appropriate doses and duration of the GSE therapy in rabbits Pasteurellosis.
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Azza Ahmed Abdelghafar Gala, "The Relationship between Gastroprotective Effect of Propolis and Its Antioxidant activity", كلية الطب البيطرى, 2010
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Azza Ahmed Abdelghafar Gala, "Clinicopathological Studies On Hepato-Nephro-Protective Effect Of Salvadora Persica Extract In Albino Rats", كلية الطب البيطرى, 2013
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Azza Ahmed Abdelghafar Gala, "Protective effect of Zingiber officinale (ginger) on doxorubicin induced oxidative cardiotoxicity in rats.", Life Science Journal, 2013
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Azza Ahmed Abdelghafar Gala, "COMARSION OF PUNICA PEEL AND OXYTETRACYCLIN ON AEROMONAS HYDROPHILA CHALLENGED CLARIAS GARIEPINUS", The Global Journal of Fisheries and Aqua. Res. - Vol. No. 5, (2012) - ISSN 18191, 2012
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Azza Ahmed Abdelghafar Gala, "Toxic effects of sub-chronic exposure of male albino rats to emamectin benzoate and possible ameliorative role of Foeniculum vulgare essential oil", Elsevier, 2015
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Department Related Publications
Ahmed Abdoh Said Muhmmd, "Effect of Corynebacterium cutis extract on the Immune response of Brucella vaccinated buffalo valves", لايوجد, 1900
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Alsayed Ahmed Abdelazeez , "Studies on the toxic effects of an aqueous extract of Astragalus kahiricus DC. orally adminstered to rats ", لايوجد, 1900
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Alsayed Ahmed Abdelazeez , "studies on the toxic effects of the aqueous extract of Euryops arabicus orally administered to rats ", لايوجد, 1900
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Sawan Mohamed Mohamed Ali Elsheakh , "The antibiotic activity of tricophyton violaceum extract.", لايوجد, 1900
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Sawan Mohamed Mohamed Ali Elsheakh , "The in-vitro effect of prostaglandin F2 alpha and oxytocin on the uterus of camel", لايوجد, 1900
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