Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Breast milk MSCs: An explanation of tissue growth and maturation of offspring
Faculty
Veterinary Medicine
Year:
2016
Type of Publication:
ZU Hosted
Pages:
Authors:
Tariq Khamis Kamal Ahmed Khamis
Staff Zu Site
Abstract In Staff Site
Journal:
IUBMB Life wiley
Volume:
Keywords :
Breast milk MSCs: , explanation , tissue growth
Abstract:
Exciting advances are revealing that breast milk harbors populations of stem and progenitor cells, and much attention is now intensified on delineating their properties and functions. The aim of this study is to isolate a mesenchymal stem cell (MSC)‐like population from rabbit breast milk and track their integration into the different organs of the breastfed rabbits after taken by oral route and to explore the functional role of stem cells in the breastfed newborn babies. Ten newborn rabbits 2 weeks old fed on 2 × 106 PKH26‐labeled rabbit milk derived‐MSCs suspended in 2 mL Dulbecco's modified Eagle's medium (DMEM) and 10 newborn baby rabbits fed with 2 mL DMEM solution or with rabbit fibroblasts as a control group were used in the study. All rabbits were sacrificed after 1 week. We found that PKH26‐labeled MSCs were engrafted into the offspring organs as liver, cartilage, bone and duodenum. Histologically, there was proliferation of cells in some organs. Moreover, there was overexpression of both PCNA and cyclin D1 genes in all organs from milk derived MSCs fed rabbits compared to the control group. Our results confirmed the presence of MSC‐like population in the breast milk. We first showed that milk derived‐MSCs were engrafted into the offspring organs when were taken orally. Milk derived‐MSCs may elucidate the functional benefits to the newborn babies by increasing cell proliferation and growth.
Author Related Publications
Tariq Khamis Kamal Ahmed Khamis, "Curative and protective potentials of decoction of Moringa oleifera leaf on the streptozotocin-Induced Diabetes mellitus in albino Rats", Iraqi Journal of Veterinary Sciences, 2022
More
Tariq Khamis Kamal Ahmed Khamis, "β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study", MDPI, 2022
More
Tariq Khamis Kamal Ahmed Khamis, "Semaglutide early intervention attenuated testicular dysfunction by targeting the GLP-1–PPAR-α–Kisspeptin–Steroidogenesis signaling pathway in a testicular ischemia-reperfusion rat model", elsevier, 2021
More
Tariq Khamis Kamal Ahmed Khamis, "Clinical implication and prognostic significance of FLT3-ITD and ASXL1 mutations in Egyptian AML patients: A single-center study", IOS press, 2021
More
Tariq Khamis Kamal Ahmed Khamis, "Anti-inflammatory, Analgesic and Ulcerogenic Potency of Curcumin in Comparison with Celecoxib and Prednisolone", Assiut University, 2021
More
Department Related Publications
Ahmed Abdoh Said Muhmmd, "Pharmacological Effects of Fish and Soyabean oils in Sheep", لايوجد, 1900
More
Ahmed Abdoh Said Muhmmd, "العلاقة بين تاثيرصمغ النحل كواقى للمعدة وقدرتة كمضاد للاكسدة ", لايوجد, 1900
More
Alsayed Ahmed Abdelazeez , "Efficacy and pharmacokinetic pattern of norfloxacin in both healthy and diseased chickens. proceeding from the 1st Conf. on The role of Scientific Research and Technological Development in the Protection of Environment Against Pollution ", لايوجد, 1900
More
Alsayed Ahmed Abdelazeez , "A prelude to the clinical use of fertagyl and prosolvin in male infertility ", لايوجد, 1900
More
Hosnah Abdelfadiel, " Biochemical, residual and histopathological studies in catfish (C. ", لايوجد, 1900
More
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف