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Natural products, the new intervention regime of metabolic disorders.
Faculty
Pharmacy
Year:
2020
Type of Publication:
ZU Hosted
Pages:
Authors:
Aseem Mohamed Mohamed Elshazly Hamouda
Staff Zu Site
Abstract In Staff Site
Journal:
Vol. 2, Chapter 2, pages 32-122 Bentham Book Imprint
Volume:
Keywords :
Natural products, , , intervention regime , metabolic disorders.
Abstract:
Nature is considered an indispensable source of natural products and natural products-derived drug leads. Over the last decade, the use of natural products-based medicine (herbal medicine or phytomedicine) has increased tremendously worldwide especially with the exceeding prevalence of metabolic disorders. Metabolic disorders are the major worldwide epidemic associated with obesity, diabetes mellitus, cardiovascular diseases associated with hyperlipidemia, and many other endocrine and nutrition-related issues. Since metabolic disorders are multi-factorial in their pathophysiology, they can be targeted by natural products that have synergy between diverse metabolites. Therefore, it is important to find the proper formulas not only for the treatment but also for reduction of associated risks and for prophylaxis and prevention of long-term complications. At the present work, a brief outline of the pathophysiology of metabolic disorders is provided. Additionally, natural product based drug therapies that are currently applied in clinical trials attributed to metabolic related diseases are critically discussed.
Author Related Publications
Aseem Mohamed Mohamed Elshazly Hamouda, "HPLC-ESI-MS/MS profiling of polyphenolics of a leaf extract from Alpinia zerumbet (Zingiberaceae) and its anti-inflammatory, anti-nociceptive, and antipyretic activities in vivo.", mdpi, 2018
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Aseem Mohamed Mohamed Elshazly Hamouda, "Anti-Inflammatory, Antipyretic, and Analgesic Properties of Potamogeton perfoliatus Extract: In Vitro and In Vivo Study", mdpi, 2021
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Aseem Mohamed Mohamed Elshazly Hamouda, "Gastro-Protective Effects of Albizia anthelmintica Leaf Extract on Indomethacin-Induced Gastric Ulcer in Wistar Rats: In Silico and In Vivo Studies", mdpi, 2021
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Aseem Mohamed Mohamed Elshazly Hamouda, "Syzygium samarangense leaf extract mitigates indomethacin-induced gastropathy via the NF-κB signaling pathway in rats", Elsevier, 2021
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Aseem Mohamed Mohamed Elshazly Hamouda, "Syzygium jambos extract mitigates pancreatic oxidative stress, inflammation and apoptosis and modulates hepatic IRS-2/AKT/GLUT4 signaling pathway in streptozotocin-induced diabetic rats", Elsevier, 2021
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Department Related Publications
Ehsan Mahmoud Abdelaziz Abozied, "Pharmacognostical study and phytochemical investigation of launaea mucronata ", لايوجد, 1900
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Ehsan Mahmoud Abdelaziz Abozied, "7) GC-MS and Antimicrobial Activity of Volatile Oil of Apium Leptophyllum (Benth). ", لايوجد, 1900
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Ehsan Mahmoud Abdelaziz Abozied, "17) Phytochemical study and Bioassay of some constituents from Heliotropium Bacciferum Forssk", لايوجد, 1900
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Ehsan Mahmoud Abdelaziz Abozied, "27) Phytochemical and Biological studies of the shells of Arachis hypogae L. Fruits (Pea Nut) Cutivated in Egypt", لايوجد, 1900
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