The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme

Faculty Pharmacy Year: 2020
Type of Publication: ZU Hosted Pages: 1-20
Authors:
Osama Ibrahim Abdou Elsabagh
Journal: Pharmaceuticals MDPI Volume: 13, 252
Keywords : , Anticancer Activity , , Bumetanide-Based Analogs , Targeting , Tumor-Associated Membrane-Bound Human    
Abstract:
The membrane-bound human carbonic anhydrase (hCA) IX is widely recognized as a marker of tumor hypoxia and a prognostic factor within several human cancers. Being undetected in most normal tissues, hCA-IX implies the pharmacotherapeutic adv
    
     
 
       

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