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The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme
Faculty
Pharmacy
Year:
2020
Type of Publication:
ZU Hosted
Pages:
1-20
Authors:
Tarek Mohamed Salah Rashad
Staff Zu Site
Abstract In Staff Site
Journal:
Pharmaceuticals MDPI
Volume:
13, 252
Keywords :
, Anticancer Activity , , Bumetanide-Based Analogs , Targeting , Tumor-Associated Membrane-Bound Human
Abstract:
The membrane-bound human carbonic anhydrase (hCA) IX is widely recognized as a marker of tumor hypoxia and a prognostic factor within several human cancers. Being undetected in most normal tissues, hCA-IX implies the pharmacotherapeutic adv
Author Related Publications
Tarek Mohamed Salah Rashad, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022
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Tarek Mohamed Salah Rashad, "New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors", mdpi, 2021
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Tarek Mohamed Salah Rashad, "Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction", Taylor & Francis Group, 2021
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Tarek Mohamed Salah Rashad, "Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition", ELSEVIER, 2021
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Tarek Mohamed Salah Rashad, "Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: Amelioration of cisplatin-induced nephrotoxicity", ELSEVIER, 2021
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Department Related Publications
Sobhi Mohamed Mahmoud Ibrahym, "Determination of some Pharmaceutical Carbonyl Compounds", لايوجد, 1900
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Mohammed Alhuseiny Abdelhamid Elsadek , "Continuation For Chemical Methods For Analysis of Some Antibiotics", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "Stability indicating spectrophotometric method for determination of Moexipril HCl ", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "Synthesis of new 1,2,4-Triazoloquinazoline derivatives as CNS modulators ", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "HPLC Determination of Amoxicillin,Metronidazole and pot. clavulanate in combination mixture in presence of their degradation products ", لايوجد, 1900
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