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The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme
Faculty
Pharmacy
Year:
2020
Type of Publication:
ZU Hosted
Pages:
1-20
Authors:
Tarek Mohamed Salah Rashad
Staff Zu Site
Abstract In Staff Site
Journal:
Pharmaceuticals MDPI
Volume:
13, 252
Keywords :
, Anticancer Activity , , Bumetanide-Based Analogs , Targeting , Tumor-Associated Membrane-Bound Human
Abstract:
The membrane-bound human carbonic anhydrase (hCA) IX is widely recognized as a marker of tumor hypoxia and a prognostic factor within several human cancers. Being undetected in most normal tissues, hCA-IX implies the pharmacotherapeutic adv
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Tarek Mohamed Salah Rashad, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022
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Department Related Publications
Mansour Alsayed Mansour Abokol, "SYNTHESIS OF 3- SUBSTITUTED (6-BROMO-2-IMIDAZO {4, 5- B} PYRIDINYL) PROPIONIC ACID AS ANTIINFLAMMATORY, ANALGESIC, AND ANTIPYTRIC AGENTS", Zag. J. Pharm. Sci., Vol. 1 No. 1 Nov. Pp 129-139 June, 1993
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Noha Ibrahiem Elsayed Mohamed Zidain, "Developing a High-performance Liquid Chromatography Method for Simultaneous Determination of Loratadine and its Metabolite Desloratadine in Human Plasma", benthamscience, 2020
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Sobhi Mohamed Mahmoud Ibrahym, "47. Hplc determination of three cephalosporines (cefipime, ceftriaxone , cefotaxime) in their bulk and dosage form", Asian J .Pharm. Ana., 2014
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Ahmed Samy Abdelsamad Abdelkhalek hilal, "Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation", Taylor and francis, 2023
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