Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors

Faculty Pharmacy Year: 2019
Type of Publication: ZU Hosted Pages: 372-382
Authors:
Tarek Mohamed Salah Rashad
Journal: European Journal of Medicinal Chemistry ELSEVIER Volume:
Keywords : Novel benzenesulfonamide , 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives , potential selective    
Abstract:
Two new series of 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives containing either five membered heterocyclic rings or aryl hydrazones were synthesized and evaluated for their in vitro COX-1/COX-2 inhibitory activity. In vivo anti-inf
    
     
 
       

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  • Amany Mohamed Mohamed Elmahmoudy Sanger, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022 More
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