Synthesis, In vivo and In silico Evaluation of Novel 2,3-Dihydroquinazolin-4(1H)-one Derivatives as Potential Anticonvulsant Agents

Faculty Pharmacy Year: 2019
Type of Publication: ZU Hosted Pages: 343-352
Authors:
Samy Megahed Ibrahiem Elsayed Sakr
Journal: Drug Development Research wiley Volume: 80
Keywords : Synthesis, , vivo , , silico Evaluation , Novel 2,3-Dihydroquinazolin-4(1H)-one    
Abstract:
In light of the pharmacophoric structural requirements for achieving anticonvulsant activity, a series of N-(1-methyl-4-oxo-2-un/substituted-1,2-dihydroquinazolin-3[4H]-yl)benzamide (4a-g) and N-(1-methyl-4-oxo-2-un/substituted-1,2-dihydroq
    
     
 
       

Author Related Publications

  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation", WILEY, 2010 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity", springer link, 2013 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS", ajrc, 2013 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium", 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2013 More

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