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Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides
Faculty
Pharmacy
Year:
2013
Type of Publication:
ZU Hosted
Pages:
Authors:
Hend Kather Abdelhakem Elhamalawy
Staff Zu Site
Abstract In Staff Site
Journal:
Bioorganic & Medicinal Chemistry Letters ELSEVIER
Volume:
Keywords :
Design, synthesis , , vitro anticancer evaluation , 4,6-diamino-1,3,5-triazine-2-carbohydrazides
Abstract:
Series of substituted 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides have been synthesised, based on molecular modelling of candidate structures related to the previously reported Rad6B-inhibitory diamino-triazinylmethyl ben
Author Related Publications
Hend Kather Abdelhakem Elhamalawy, "Preclinical evaluation of Rad6 inhibition to overcome platinum resistance in ovarian cancer", AACR, 2016
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Hend Kather Abdelhakem Elhamalawy, "Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation", WILEY interscience, 2010
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Hend Kather Abdelhakem Elhamalawy, "Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity", springer link, 2013
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Hend Kather Abdelhakem Elhamalawy, "Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization", AACR publications, 2013
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Hend Kather Abdelhakem Elhamalawy, "RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance", Springer Nature., 2017
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Department Related Publications
Abdallah Ahmed Abdallah Elshanawany, "Development and validation of liquid chromatographic method for simultaneous determination of amiloride hydrochloride and hydrochlorothiazide in human urine", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "HPLC Determination of polymyxin sulphate, Benzalkonium chloride, and gramicidine in pharm.formulation ", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "Synchronous Spectroflurimetric Determination of Famtidine,Fluconazole and Ketoconazole in bulk powder and in pharmaceutical dosages forms ", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "Synthesis of 3- substituted (6-bromo-2-imidazo{4,5-b}pyridinyl)propionic acid as antiinflammatory agents. ", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "Application of difference spectrophotometry to the nitrosation reaction in the assay of certain antipyretic drugs . ", لايوجد, 1900
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