Design, synthesis, anticonvulsant activity, and pharmacophore study of new 1,5-diaryl-1H-1,2,4-triazole-3-carboxamide derivatives

Faculty Veterinary Medicine Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Sameh Mohamed Mostafa Elnbtete
Journal: Medicinal Chemistry Research Springer Volume:
Keywords : Design, synthesis, anticonvulsant activity, , pharmacophore study    
Abstract:
Diaryl-1H-1,2,4-triazole-3-carboxamide derivatives were designed, synthesized, and evaluated for its anticonvulsant activity using maximal electroshock (MES) and chemoshock (scPTZ and Strychnine) animal screen methods. Neurotoxicity was als
    
     
 
       

Author Related Publications

  • Sameh Mohamed Mostafa Elnbtete , "دراسة مقارنة لاثنين من مضادات الاكسدة", لايوجد, 1900 More
  • Sameh Mohamed Mostafa Elnbtete , "Synthesis and Pharmacological Studies for New Benzotriazole and Dibenzodiazepine Derivatives as Antipsychotic Agents", Springer Nature, 2009 More
  • Sameh Mohamed Mostafa Elnbtete , "Biological activities of new salts of 2-carboxyphenyloxamoylamino acids", Springer Nature, 2015 More
  • Sameh Mohamed Mostafa Elnbtete , "Synthesis and Some Pharmacological Studies of New Benzenesulfonamide Derivatives", Springer Nature, 2002 More
  • Sameh Mohamed Mostafa Elnbtete , "Synthesis and Biological Activities of 2-Carboxyphenyloxamoylamino Acids, their Salts with 2-ethoxy-6,9-Diaminoacridine and D-glucosamine", Springer Nature, 2013 More

Department Related Publications

  • Azza Mohamed Ali Abo El-Maati, "Effects of different feeding regimens with protease supplementation on growth, amino acid digestibility, economic efficiency, blood biochemical parameters, and intestinal histology in broiler chickens", Springer nature, 2021 More
  • Azza Mohamed Ali Abo El-Maati, "Thymol alleviates imidacloprid-induced testicular toxicity by modulating oxidative stress and expression of steroidogenesis and apoptosis-related genes in adult male rats", Elsevier Inc, 2021 More
  • Nabila Emam Alsharkawy, "Early postmortem biochemical, histological, and immunohistochemical alterations in skeletal muscles of rats exposed to boldenone undecylenate: Forensic implication", Elsevier Inc, 2021 More
Tweet