RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages:
Authors:
Hend Kather Abdelhakem Elhamalawy
Journal: Oncogene Springer Nature. Volume:
Keywords : RAD6 promotes , repair , stem cell signaling    
Abstract:
Ovarian cancer (OC) is the most deadly gynecological cancer and unlike most other neoplasms, survival rates for OC have not significantly improved in recent decades. We show that RAD6, an ubiquitin-conjugating enzyme, is significantly over
    
     
 
       

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