Synthesis and Anticancer Studies of Novel N-Benzyl Pyridazinone Derivatives

Faculty Pharmacy Year: 2017
Type of Publication: ZU Hosted Pages: 1008-1013
Authors:
Tarek Mohamed Salah Rashad
Journal: Letters in Drug Design & Discovery Bentham Science Publishers Volume: 14
Keywords : Synthesis , Anticancer Studies , Novel N-Benzyl Pyridazinone Derivatives    
Abstract:
Introduction: According to WHO, cancer is one of the most leading causes of death. Development of anticancer drugs draw considerable attention. Pyridazinones analogues were reported to possess anticancer properties. Chemical modification
    
     
 
       

Author Related Publications

  • Tarek Mohamed Salah Rashad, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022 More
  • Tarek Mohamed Salah Rashad, "New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors", mdpi, 2021 More
  • Tarek Mohamed Salah Rashad, "Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction", Taylor & Francis Group, 2021 More
  • Tarek Mohamed Salah Rashad, "Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition", ELSEVIER, 2021 More
  • Tarek Mohamed Salah Rashad, "Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: Amelioration of cisplatin-induced nephrotoxicity", ELSEVIER, 2021 More

Department Related Publications

  • Etedaal Hassan Mohamed Abdulaal, "14. Reaction of 2-Ethyl Thiohydantions with Anthranilic Acid", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "9. A New Derivatives from Thiolanes and Thietanes; ", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "10. Anti-inflammatory Activity of Some Novel-s- Triazole Derivatives", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "21. Synthesis, Antimicrobial and Antiviral Activity of 1,8-Dioxodecahydroacridine Derivatives", لايوجد, 1900 More
  • Etedaal Hassan Mohamed Abdulaal, "25. Synthesis And Anti-inflammatory Activity of Some Novel Quinazoline Derivatives", لايوجد, 1900 More
Tweet