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Synthesis, Anticonvulsant Activity and Cytotoxicity of Novel Valproic Acid Derivatives
Faculty
Pharmacy
Year:
2017
Type of Publication:
ZU Hosted
Pages:
33-40
Authors:
Tarek Mohamed Salah Rashad
Staff Zu Site
Abstract In Staff Site
Journal:
IOSR Journal of Applied Chemistry (IOSR-JAC) www.iosrjournals.org
Volume:
5
Keywords :
Synthesis, Anticonvulsant Activity , Cytotoxicity , Novel Valproic
Abstract:
Objective: The aim of this work was to construct novel hydrazones and thiosemsicarbazide derivatives of valproic acid. The new targets will be evaluated for their anticonvulsant activity and cytotoxicity effects. Methods: Targets 7a-k, 10.
Author Related Publications
Tarek Mohamed Salah Rashad, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022
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Tarek Mohamed Salah Rashad, "New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors", mdpi, 2021
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Department Related Publications
Amany Mohamed Mohamed Elmahmoudy Sanger, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022
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Amany Mohamed Mohamed Elmahmoudy Sanger, "Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates", mdpi, 2022
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Tarek Mohamed Salah Rashad, "New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors", mdpi, 2021
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