One hundred and twenty random samples of each of small scale ice cream and large scale ice cream samples collected from groceries , peddlers and supermarkets in Sharkia Governorate were examined for their sanitary condition.-The results of methylene blue reduction test of examined ice cream samples revealed that 11 of examined small scale samples (9.2%) were graded I, while 28 ( 23.3% ), 57 ( 47.5% ) and 24 ( 20% ) were graded II , III and IV respectively. But in case of exa-The bacteriological examination of ice cream samples showed that mean coliform count/g. in examined small scale samples was 4.3×106 ,4.9×106 and 3.2×106 for plain , fruit and chocolate ice creamsamples respectively,while coliform organisms in examined la-The most prevalent Coliform species isolated from examined small scale ice cream samples were Citrobacter Freundii ,Enterobacter Aerogenes Enterobacter Cloacae,Erwinia The present study was carried out to investigate the toxiceffect of xenoestrogenic compound BP A on the chromosomes ofbone marrow cells, male reproduction and histopathological picture(examination) of different organs in exposed immature and maturemale albino rats.Cytotoxic effect of BP A:The results of the cytogenetic studies with BP A that orallyadministrated to immature and mature male albino rat at dose level20}lg/kg b.wt/ day for 65 day revealed that BP A is genotoxic agent,where there was an increase in the mean value of total structuralchromosomal aberrations in the form of break, gap, centromericattenuation, deletions ,ring chromosome, end to end associationand sticky chromosomes. In addition to increase in the mean valueof numerical chromosomal aberration in the form of hypoploidy inboth immature and mature groups when compared treated withtheir corresponding control group.