SYNTHESIS OF NEW PYRIMIDINE DERIVATIVES AND EVALUATION OF THEIR ANTICANCER AND ANTIMICROBIAL ACTIVITIES

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages: 306-313
Authors:
Nermeen Awny Ahmed Mohamd
Journal: Asian Journal of Pharmaceutical and Clinical Research Innovare Volume:
Keywords : SYNTHESIS , , PYRIMIDINE DERIVATIVES , EVALUATION , THEIR ANTICANCER AND    
Abstract:
The objective of this work is to synthesize new pyrimidine derivatives starting from ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate. Several oxadiazole, triazole and thiadiazole moieties were incorporated to the pyrimidine backbone. The structu
    
     
 
       

Author Related Publications

  • Nermeen Awny Ahmed Mohamd, "Synthesis of some new Pyrazole Derivatives of Possible Biological Interest", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrimidine derivatives ", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrazole derivatives", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Utility of 2-Hydrazino-4,6-Dimethyl –Pyrimidine in Heterocyclic Synthesis ", لايوجد, 1900 More
  • Nermeen Awny Ahmed Mohamd, "Design, synthesis and in-vitro antitumor activity of novel phthalazin-1,4-dione/chalcone hybrids and phthalazin-1,4-dione/pyrazoline hybrids", JCPRC5, 2015 More

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  • Zakareyah Kamel Abdelsamie, "Synthesis of some novel s-triazolo[3,4-b]-1,3,4-thiadiazole derivatives as antiinflammatory agents", Proceedings of XXI conference of Pharmaceutical Sciences, 1990 More
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