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SYNTHESIS OF NEW PYRIMIDINE DERIVATIVES AND EVALUATION OF THEIR ANTICANCER AND ANTIMICROBIAL ACTIVITIES
Faculty
Pharmacy
Year:
2016
Type of Publication:
ZU Hosted
Pages:
306-313
Authors:
Nermeen Awny Ahmed Mohamd
Staff Zu Site
Abstract In Staff Site
Journal:
Asian Journal of Pharmaceutical and Clinical Research Innovare
Volume:
Keywords :
SYNTHESIS , , PYRIMIDINE DERIVATIVES , EVALUATION , THEIR ANTICANCER AND
Abstract:
The objective of this work is to synthesize new pyrimidine derivatives starting from ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate. Several oxadiazole, triazole and thiadiazole moieties were incorporated to the pyrimidine backbone. The structu
Author Related Publications
Nermeen Awny Ahmed Mohamd, "Synthesis of some new Pyrazole Derivatives of Possible Biological Interest", لايوجد, 1900
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Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrimidine derivatives ", لايوجد, 1900
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Nermeen Awny Ahmed Mohamd, "Synthesis and Anti-inflammatory activity of Novel Pyrazole derivatives", لايوجد, 1900
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Nermeen Awny Ahmed Mohamd, "Utility of 2-Hydrazino-4,6-Dimethyl –Pyrimidine in Heterocyclic Synthesis ", لايوجد, 1900
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Nermeen Awny Ahmed Mohamd, "Design, synthesis and in-vitro antitumor activity of novel phthalazin-1,4-dione/chalcone hybrids and phthalazin-1,4-dione/pyrazoline hybrids", JCPRC5, 2015
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Department Related Publications
Tarek Mohamed Salah Rashad, "Efficient Synthesis and Computational Studies of Useful Guanylating Agents: 1H-Benzotriazole-1-carboximidamides", Wiley-VCH GmbH, 2020
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Tarek Mohamed Salah Rashad, "Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold", 2020 Elsevier, 2020
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Tarek Mohamed Salah Rashad, "Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors", ELSEVIER, 2019
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Tarek Mohamed Salah Rashad, "Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids.", Wiely, 2019
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Yasmina Elsayed Mohamed Mansour Lashien, "synthesis molecular docking and anti inflammatory screening of novel quinoline incorporated pyrazole derivatives using Pfitzinger reaction II", Bioorganic Chemistry, 2014
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