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SYNTHESIS OF NEW PYRIMIDINE DERIVATIVES AND EVALUATION OF THEIR ANTICANCER AND ANTIMICROBIAL ACTIVITIES
Faculty
Pharmacy
Year:
2016
Type of Publication:
ZU Hosted
Pages:
Authors:
Amany Mohamed Mohamed Elmahmoudy Sanger
Staff Zu Site
Abstract In Staff Site
Journal:
Asian J Pharm Clin Res www.ajpcr.com
Volume:
Keywords :
SYNTHESIS , , PYRIMIDINE DERIVATIVES , EVALUATION , THEIR ANTICANCER AND
Abstract:
Objectives: The objective of this work is to synthesize new pyrimidine derivatives starting from ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate. Several oxadiazole, triazole, and thiadiazole moieties were incorporated into the pyrimidine backb
Author Related Publications
Amany Mohamed Mohamed Elmahmoudy Sanger, "Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors", mdpi, 2022
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Amany Mohamed Mohamed Elmahmoudy Sanger, "Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates", mdpi, 2022
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Amany Mohamed Mohamed Elmahmoudy Sanger, "Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents", Bentham Science Publishers, 2022
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Amany Mohamed Mohamed Elmahmoudy Sanger, "DOCKING, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL PYRAZOLINE DERIVATIVES AS POTENTIAL ANTIMICROBIAL AND ANTITUMOR AGENTS", www.wjpr.net, 2016
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Amany Mohamed Mohamed Elmahmoudy Sanger, "SYNTHESIS OF NOVEL PYRIMIDINE AND FUSED PYRIMIDINE DERIVATIVES AND THEIR IN VITRO ANTIMICROBIAL AND CYTOTOXIC EVALUATION", www.wjpr.net, 2017
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Department Related Publications
Tarek Mohamed Salah Rashad, "Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids.", Wiely, 2019
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Tarek Mohamed Salah Rashad, "Fluoroquinolone-3-carboxamide Amino Acid Conjugates: Synthesis, Antibacterial Properties And Molecular Modeling Studies", Bentham Science Publishers, 2021
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Hanan Abdelraziek Abdelfattah Ali Hamied, "" تشييد بعض مشتقات البيرميدين الجديدة ذات النشاط الأقربازيني "", 2024
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Amany Mohamed Mohamed Elmahmoudy Sanger, "Development of Isatin-Based Schiff Bases Targeting VEGFR2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies", Wiley-VCH GmbH, 2022
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Tarek Mohamed Salah Rashad, "Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR coagonist: simulation-guided analogue design and pharmacological screening", Taylor & Francis Group, 2022
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