Antioxidative defenses system in cells and tissues against free radical includes the antioxidant nutrients and metalloenzymes such as GSH-PX, catalase, SOD and ceruloplasmin. The most important lipid phase antioxidant is Vitamin E. It was aimed from the cNinety male albino rats (200-225 gm) were used in this study. The animals were produced from Central Animal House of Faculty of Veterinary Medicine, Zagazig University. They were housed in stainless steel cages in the biochemistry department under hygieni