Systemically Administered RNAi Molecule Sensitizes Malignant Pleural Mesotheliomal Cells to Pemetrexed Therapy

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages: 3955-3963
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: Molecular Pharmaceutics ACS Publications Volume:
Keywords : Systemically Administered RNAi Molecule Sensitizes Malignant Pleural    
Abstract:
Pemetrexed (PMX) is a key drug for the management of malignant pleural mesothelioma (MPM). However, its therapeutic efficacy is cruelly restricted in many clinical settings by the overexpression of thymidylate synthase (TS) gene. Recent
    
     
 
       

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