Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages: 1399-1407
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: International Journal of Oncology Spandidos Publications Volume:
Keywords : Downregulation , thymidylate synthase , RNAi molecules enhances , antitumor    
Abstract:
Malignant pleural mesothelioma (MPM) is an incurable cancer with an increasing incidence. Currently, pemetrexed (PMX)-based chemotherapy is the mainstay of chemotherapy for MPM, however, the outcome of PMX-based chemotherapy in patients
    
     
 
       

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