Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages:
Authors:
Walid Mohamed Adel Abdelaziem Abdallah Barakat
Journal: European Journal of Pharmacology Science Direct Volume:
Keywords : Insights , , mechanism underlying , protective effect , α-lipoic    
Abstract:
Acetaminophen (APAP) is one of the most widely used analgesic antipyretic drugs and is a major cause of acute liver failure at overdose. The aim of this study is to investigate the possible protective effect of α-lipoic acid (α-LA, 20 or 10
    
     
 
       

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