Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity

Faculty	Pharmacy	Year:	2014
Type of Publication:	ZU Hosted	Pages:
Authors:	Waleed Mohamed Adel Abdelaziem Abdallah Barakat Staff Zu Site Abstract In Staff Site
Journal:	European Journal of Pharmacology Science Direct	Volume:

Keywords :	Insights , , mechanism underlying , protective effect , α-lipoic
Abstract:	Acetaminophen (APAP) is one of the most widely used analgesic antipyretic drugs and is a major cause of acute liver failure at overdose. The aim of this study is to investigate the possible protective effect of α-lipoic acid (α-LA, 20 or 10

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