Pentoxifylline abrogates cardiotoxicity induced by the administration of a single high dose or multiple low doses of doxorubicin in rats

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Shimaa Mostafa Mostafa Elshazly
Journal: Can J Physiol Pharmacol Can J Physiol Pharmacol Volume:
Keywords : Pentoxifylline abrogates cardiotoxicity induced , , administration , , single    
Abstract:
Doxorubicin (DOX) possesses a broad-spectrum antineoplastic activity; however, its clinical application is impeded by cardiotoxicity. This study aimed to investigate the protective effect of pentoxifylline (PXF), which possesses antioxidant
    
     
 
       

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  • Shimaa Mostafa Mostafa Elshazly, "The selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against myocardial ischemia reperfusion injury in rats: involvement of redox and inflammatory cascades", Naunyn-Schmiedeberg's Arch Pharmacol, 2012 More
  • Shimaa Mostafa Mostafa Elshazly, "Anticancer activity of salicin and fenofibrate.", zagizag, 2017 More
  • Shimaa Mostafa Mostafa Elshazly, "Ursodeoxycholic acid ameliorates fructose-induced metabolic syndrome in rats.", Springer-Verlag Berlin Heidelberg, 2015 More
  • Shimaa Mostafa Mostafa Elshazly, "Insights in the mechanism underlying the protective effect of α-lipoic acid against acetaminophen-hepatotoxicity.", elsevier, 2015 More
  • Shimaa Mostafa Mostafa Elshazly, "Antifibrotic activity of hesperidin against dimethylnitrosamine induced liver fibrosis in rats.", Springer-Verlag Berlin Heidelberg, 2015 More

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