Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages:
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: Drug Delivery and Translational Research Springer Volume:
Keywords : Improved intratumoral delivery , PEG-coated siRNA-lipoplexes , combination with    
Abstract:
Abstract Efficient systemic siRNA delivery to cells in the target tissue is a current critical challenge in the drug delivery field. Several studies have demonstrated that nanoparticles such as polyethylene glycol (PEG)-coated siRNA-lipo
    
     
 
       

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  • Amr Selim Ahmed Ali Abu Lila, "Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production", nature, 2014 More
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  • Amr Selim Ahmed Ali Abu Lila, "Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection", MDPI, 2021 More
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  • Amr Selim Ahmed Ali Abu Lila, "Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer", MDPI, 2021 More

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