B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages:
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: Journal of Controlled Release Elsevier Volume:
Keywords : , cell-intrinsic toll-like receptor , , responsible , , enhanced anti-PEG , production    
Abstract:
Recently, we reported that immunostimulatory siRNA-containing PEGylated lipoplex (PEGylated siRNAlipoplex) activates the immune system, resulting in the enhanced production of anti-PEG IgM. However, the enhancing mechanism upon anti-PEG I
    
     
 
       

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