Application of Polyglycerol Coating to Plasmid DNA Lipoplex for the Evasion of the Accelerated Blood Clearance Phenomenon in Nucleic Acid Delivery

Faculty Pharmacy Year: 2014
Type of Publication: ZU Hosted Pages: 557-566
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: Journal of Pharmaceutical Sciences Wiley Volume:
Keywords : Application , Polyglycerol Coating , Plasmid , Lipoplex for the    
Abstract:
ABSTRACT: Cationic liposomes (CLs) have shown promise as nonviral delivery systems. To achieve in vivo stability and long circulation, most liposomes are modified with hydrophilic polymer polyethylene glycol (PEG). However, we have reporte
    
     
 
       

Author Related Publications

  • Amr Selim Ahmed Ali Abu Lila, "Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production", nature, 2014 More
  • Amr Selim Ahmed Ali Abu Lila, "Treatment of pulmonary arterial hypertension by vardenafil-solid dispersion lozenges as a potential alternative drug delivery system", Elsevier, 2020 More
  • Amr Selim Ahmed Ali Abu Lila, "Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Efficacy of SPG-ODN 1826 Nanovehicles in Inducing M1 Phenotype through TLR-9 Activation in Murine Alveolar J774A.1 Cells: Plausible Nano-Immunotherapy for Lung Carcinoma", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer", MDPI, 2021 More

Department Related Publications

  • Mahmoud Mokhtar AhmedIbrahiem, "Phase Study and Characterization of Certain Developed Multicomponent Colloidal Systems and their Potential Application As Carriers for An Antimicrobial Agent", لايوجد, 1900 More
  • Amr Selim Ahmed Ali Abu Lila, "Ex-vivo/in-vitro anti-polyethylene glycol (PEG) immunoglobulin M production from murine splenic B cells stimulated by PEGylated liposome", J.Stage, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model: synergy or antagonism?", Elsevier, 2012 More
  • Azza Ali Hassan Solyman, "Formulation and evaluation of metformin hydrochloride-loaded niosomes as controlled release drug delivery system", Informa health, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model", Elsevier, 2009 More
Tweet