Multiple administration of PEG-coated liposomal oxaliplatin enhances its therapeutic efficacy: a possible mechanism and the potential for clinical application

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages: 176-83
Authors:
Amr Selim Ahmed Ali Abu Lila
Journal: International Journal of Pharmaceutics Elsevier Volume: 1-2
Keywords : Multiple administration , PEG-coated liposomal oxaliplatin enhances    
Abstract:
We previously developed a PEG-coated cationic liposome that enabled dual targeting delivery of oxaliplatin (l-OHP) to both tumor endothelial cells and tumor cells in a solid tumor. The targeted liposomal l-OHP formulation consequently elici
    
     
 
       

Author Related Publications

  • Amr Selim Ahmed Ali Abu Lila, "Activation of TLR9 by incorporated pDNA within PEG-coated lipoplex enhances anti-PEG IgM production", nature, 2014 More
  • Amr Selim Ahmed Ali Abu Lila, "Treatment of pulmonary arterial hypertension by vardenafil-solid dispersion lozenges as a potential alternative drug delivery system", Elsevier, 2020 More
  • Amr Selim Ahmed Ali Abu Lila, "Doxorubicin Embedded into Nanofibrillated Bacterial Cellulose (NFBC) Produces a Promising Therapeutic Outcome for Peritoneally Metastatic Gastric Cancer in Mice Models via Intraperitoneal Direct Injection", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Efficacy of SPG-ODN 1826 Nanovehicles in Inducing M1 Phenotype through TLR-9 Activation in Murine Alveolar J774A.1 Cells: Plausible Nano-Immunotherapy for Lung Carcinoma", MDPI, 2021 More
  • Amr Selim Ahmed Ali Abu Lila, "Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer", MDPI, 2021 More

Department Related Publications

  • Mahmoud Mokhtar AhmedIbrahiem, "Phase Study and Characterization of Certain Developed Multicomponent Colloidal Systems and their Potential Application As Carriers for An Antimicrobial Agent", لايوجد, 1900 More
  • Amr Selim Ahmed Ali Abu Lila, "Ex-vivo/in-vitro anti-polyethylene glycol (PEG) immunoglobulin M production from murine splenic B cells stimulated by PEGylated liposome", J.Stage, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model: synergy or antagonism?", Elsevier, 2012 More
  • Azza Ali Hassan Solyman, "Formulation and evaluation of metformin hydrochloride-loaded niosomes as controlled release drug delivery system", Informa health, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model", Elsevier, 2009 More
Tweet