The co-delivery of oxaliplatin abrogates the immunogenic response to PEGylated siRNA-lipoplex

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages: 2344-54
Authors:
Journal: Pharmaceutical Research springer Volume: 9
Keywords : , co-delivery , oxaliplatin abrogates , immunogenic response , PEGylated    
Abstract:
PURPOSE: In vivo application of siRNA/PEGylated cationic liposome complex (lipoplex) is impeded by two main obstacles: cytokine responses and anti-PEG IgM responses to PEGylated siRNA-lipoplex. Here, we investigated whether co-administra
   
     
 
       

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