Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity

Faculty Pharmacy Year: 2013
Type of Publication: ZU Hosted Pages:
Authors:
Hend Kather Abdelhakem Elhamalawy
Journal: Medicinal chemistry Research springer link Volume:
Keywords : Synthesis , , benzotriazepin-5(2H)-one derivatives , expected antipsychotic activity    
Abstract:
A new series of 3,4-dihydro-1H-benzo[e][1,2,4] triazepin-5(2H)-one derivatives were synthesized by cyclocondensation of benzohydrazides (II, IX), derived from the reaction ofN-methyl-isatoic anhydride with phenyl hydrazine and isonicoti
    
     
 
       

Author Related Publications

  • Hend Kather Abdelhakem Elhamalawy, "Preclinical evaluation of Rad6 inhibition to overcome platinum resistance in ovarian cancer", AACR, 2016 More
  • Hend Kather Abdelhakem Elhamalawy, "Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides", ELSEVIER, 2013 More
  • Hend Kather Abdelhakem Elhamalawy, "Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation", WILEY interscience, 2010 More
  • Hend Kather Abdelhakem Elhamalawy, "Novel Inhibitors of Rad6 Ubiquitin Conjugating Enzyme: Design, Synthesis, Identification, and Functional Characterization", AACR publications, 2013 More
  • Hend Kather Abdelhakem Elhamalawy, "RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance", Springer Nature., 2017 More

Department Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and biological activity of 2,5-diaryl-3-methyl-pyrimidino[4,5-c]quinolin-1(2H)-one derivatives", Elsevier, 2007 More
  • Kamel Abdelrehem Metwaly Bayomy, ". Synthesis, in-vitro Cytotoxicity, and a Preliminary Structure-Activity Relationship Investigation of Pyrimido[4,5-c]quinolin-1(2H)-ones", Wiley-Interscience, 2010 More
  • Ahmed Samy Abdelsamad Abdelkhalek hilal, "Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية", 2024 More
  • Samy Megahed Ibrahiem Elsayed Sakr, "Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية", 2024 More
  • Mansour Alsayed Mansour Abokol, "Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية", 2024 More
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