| Abstract: |
V. SUMMARY AND CONCLUSIONThe approximate chemical composition of (Corcuma Longa Coriandrum Sativum and Solanum Nigrum) was studied. Oil and protein content of (Corcuma Longa, Coriandrum Sativum and Solanum Nigrum) were (7.2 %, 12.3 % and 1.3 %) for oil content, while it were (3.7%, 5.3 % and 4.5 %) for protein content, respectively.The preliminary phytochemical screening showed that the studied plants were rich in flavonoids. Eethanolic extract of the studied plants were showed the scavenging activity on DPPH radicals. The data showed that the (Corcuma longa, Coriandrum sativum and Solanum nigrum) were (53.2 %, 56.32 % and 55.29 %).An experiment was carried out by using 30 male albino rats which were divided into five groups after adaptation period (7 days). The negative control (6 rats) was fed on basal diet, while positive control was fed on a hyperlipidaemic diet. The treated groups were fed on hyperlipidaemic diets supplemented with 8 % of each of (Corcuma longa, Coriandrum sativum and Solanum nigrum) respectively. The duration period of the experiment was nine weeks. At the end of the experiment the body weight gain, liver, kidneys functions and lipid pattern were determined. It was found that the addition of all plants gave the highest significant decrease in total lipid, total cholesterol, and triglycerides. Other plants also significantly decrease all these parameters but in different degrees. HDL-cholesterol, LDL-cholesterol, VLDL-cholesterol, chylomicro-naemia, atherogenic index and ratio of LDL-cholesterol/HDL-cholesterol was also determined in rat’s serum. Most organs functions were improved and attained nearly to the negative control group as S.G.O.T., S.G.P.T., S.G.O.T./S.G.P.T. ratio, s. albumin, s. total protein, s. globulin, s. total bilirubin, albumin/globulin ratio, s. uric acid and blood urea. Also, s. glucose was nearly returned the negative control group.The obtained results could be summarized as follow:Improving knowledge of the biological effect of natural substances plants would assist in the efforts to achieve the curing effect of these plants. Optioned data about its role as a hypocholesterolemic agent gives us valuable information about its biological role. The (Coriandrum sativum, Solanum nigrum and Corcuma longa) plants can play a hypocholesterolemic role against hyperlipidaemia disease in concentration of (8 %) with diets. The possible role of such plants may be from its contents of active components which may play as antioxidants, attack free radical, improve lipid pattern and organs function. So that this plants considered as a new non-conventional supply for the pharmaceutical industries and for edible purposes..
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