Zagazig University Digital Repository
Home
Thesis & Publications
All Contents
Publications
Thesis
Graduation Projects
Research Area
Research Area Reports
Search by Research Area
Universities Thesis
ACADEMIC Links
ACADEMIC RESEARCH
Zagazig University Authors
Africa Research Statistics
Google Scholar
Research Gate
Researcher ID
CrossRef
Serum concentrations and tissue residues of spectinomycin in chickens.
Faculty
Veterinary Medicine
Year:
1995
Type of Publication:
Article
Pages:
446-450
Authors:
ElSayed, MGA, ElAziz, MI, ElKomy, AAA, ElDin, HS
Journal:
DEUTSCHE TIERARZTLICHE WOCHENSCHRIFT M H SCHAPER GMBH CO KG
Volume:
102
Research Area:
Veterinary Sciences
ISSN
ISI:A1995TM00200008
Keywords :
Serum concentrations , tissue residues , spectinomycin , chickens.
Abstract:
Following a single intramuscular injection of 40 mg spectinomycin/kg.b.wt. in normal chickens, a maximum serum concentration was recorded at one hour, with half-lives of absorption {[}t(0.5(ab))] and elimination {[}t(0.5(beta))] valued with 0.21 h and 3.27 h respectively. Following a single intravenous injection of 40 mg spectinomycin/kg b. wt. in normal chickens, the drug obeyed a three compartments open model. The mean systemic bioavailability following intramuscular injection was 3.72 \%. The highest serum concentration of spectinomycin was achieved after one hour post each intramuscular dose during multiple dosage regimen. Serum and tissue concentrations of spectinomycin in slaughtered normal chickens following repeated intramuscular administration, three times daily for five consecutive days were investigated. In the present study, spectinomycin was bound in vitro with normal chicken serum protein at a level equal to 5.4 \%.
Online
PDF
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف