Some important uridine reactions

The presented study concern some reactions on the 5-position of uridine such as reaction 2',3'-O-isopropylidene uridine with 5-bromofuran-2-carbaldehyde. The reactions of uridine with thioaldehydes are of a cycle addition character. Furthermore, reaction of uridine with thiobenzoic acid is an addition reaction on the 5,6 double bond of the heterobase. Nucleophilic substitution of the thiobenzoyl group of the resulting product by ethyl or t-butyl glycine esters was performed.